DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2656 and fet5

DIOPT Version :9

Sequence 1:	NP_649699.1	Gene:	CG2656 / 40857	FlyBaseID:	FBgn0037478	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_594965.1	Gene:	fet5 / 2543397	PomBaseID:	SPAC4D7.12c	Length:	276	Species:	Schizosaccharomyces pombe

Alignment Length:	287	Identity:	127/287 - (44%)
Similarity:	182/287 - (63%)	Gaps:	17/287 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRFAQIIVGPAGSGKSTYCSLMQQYAMDCKRNVQVVNLDPAAEHFTYNPLTDIRDLIHLDDAMED 65
            ::.|..:.|.|.|||||:|..:..|.....|:..:||||||||:|.:.|..||||||.:||.|
pombe     2 VKVAAFVCGVASSGKSTFCGALMSYMKSVGRSCHLVNLDPAAENFEWEPTVDIRDLISIDDVM-- 64

  Fly    66 EELHYGPNGGLIFCLEFLIENQEWLKEQLCGGENELMVGEPDDDYILFDMPGQIELFTHLKMGRQ 130
            |||.||||||||:|.|||:||.:||.|:         :|:.|:||::|||||||||:||:.:...
pombe    65 EELDYGPNGGLIYCFEFLMENLDWLNEE---------IGDYDEDYLIFDMPGQIELYTHVPILPA 120

  Fly   131 LVELLE-SWNFRTCVVFCLDSQFMVDGAKFISGTMAALSVMANMEQPHINVLTKVDLLSSD---A 191
            |:..|: :.|||.|.|:.|:|||:||..||.:|.::|:|.|..||.||||:|:|:|||..:   .
pombe   121 LIRHLQVTLNFRPCAVYLLESQFLVDRTKFFAGVLSAMSAMVMMEVPHINLLSKMDLLKDNNNIT 185

  Fly   192 RKQLEMYLEPDAHSLMGELTIGTGFGEKYAKLTQAIGALIEDFSLVRFFPLDSQDEESVGDLLLQ 256
            :.:|:.:|..|...|.||:...|  ..|:.:|.:.|..||:||::|.|.||:|.:||||..:|..
pombe   186 KAELKRFLNTDPLLLTGEINETT--NPKFHELNRCIVQLIDDFNMVNFLPLESGNEESVSRVLSY 248

  Fly   257 IDSILQYGEDADVNVKDFDEPEEGDQD 283
            ||...|:.||.:....|..|.::.:.|
pombe   249 IDDATQWYEDQEPKDPDRFEADDLEDD 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2656	NP_649699.1	Gem1	2..196	CDD:224025	95/197 (48%)
CG2656	NP_649699.1	ATP_bind_1	7..263	CDD:281079	120/259 (46%)
fet5	NP_594965.1	Gem1	1..197	CDD:224025	97/205 (47%)
fet5	NP_594965.1	ATP_bind_1	8..255	CDD:281079	120/259 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	229	1.000	Domainoid score	I508
eggNOG	1	0.900	-	-		E1_KOG1534
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6487
Inparanoid	1	1.050	237	1.000	Inparanoid score	I834
OMA	1	1.010	-	-		QHG53962
OrthoFinder	1	1.000	-	-		FOG0004799
OrthoInspector	1	1.000	-	-		oto101804
orthoMCL	1	0.900	-	-		OOG6_102080
Panther	1	1.100	-	-	LDO	PTHR21231
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R521
SonicParanoid	1	1.000	-	-		X3381
TreeFam	1	0.960	-	-
	14	13.860