DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2656 and Y75B8A.14

DIOPT Version :9

Sequence 1:	NP_649699.1	Gene:	CG2656 / 40857	FlyBaseID:	FBgn0037478	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_499587.1	Gene:	Y75B8A.14 / 176649	WormBaseID:	WBGene00013550	Length:	272	Species:	Caenorhabditis elegans

Alignment Length:	283	Identity:	137/283 - (48%)
Similarity:	197/283 - (69%)	Gaps:	14/283 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRFAQIIVGPAGSGKSTYCSLMQQYAMDCKRNVQVVNLDPAAEHFTYNPLTDIRDLIHLDDAMED 65
            |::||:::||||||||||||:|..:.:...|.:::||||||.|.|.|..:.|:||||.::|..||
Worm     1 MKYAQLVMGPAGSGKSTYCSVMYNHCLSTGRTLRMVNLDPACEVFNYPAVVDVRDLISVNDVQED 65

  Fly    66 EELHYGPNGGLIFCLEFLIENQEWLKEQLCGGENELMVGEPDDDYILFDMPGQIELFTHLKMGRQ 130
            |||..||||.|:||:|:|::|.|||.::|..||         |||.:.|.||||||::||.:.||
Worm    66 EELILGPNGALVFCMEYLVQNLEWLHDELDEGE---------DDYFVIDCPGQIELYSHLPVMRQ 121

  Fly   131 LVELLESWNFRTCVVFCLDSQFMVDGAKFISGTMAALSVMANMEQPHINVLTKVDLLSSDARKQL 195
            :|:.|:||:|..|.||.:|:.|::|..|||||.:.|||.|..:|.|.||||||:||||...::.:
Worm   122 IVDALKSWDFNVCSVFLIDTNFVLDAEKFISGALTALSAMVAIETPAINVLTKMDLLSERNKQLV 186

  Fly   196 EMYLEPDAHSLMGELTIGTGFGEKYAKLTQAIGALIEDFSLVRFFPLDSQDEESVGDLLLQIDSI 260
            :.:||.|..|::.:  ..|.:..|:.|||:.|..::||:|:|:|.||:.:||||:..|||.||:.
Worm   187 DEFLETDTRSIVDQ--DETVWNSKHRKLTRTIAQVLEDYSIVKFVPLNCEDEESIDQLLLTIDTT 249

  Fly   261 LQYGEDADVNVKDFDEPEEGDQD 283
            :||||  |:.||| ..|||.|.:
Worm   250 IQYGE--DLEVKD-HYPEELDPE 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2656	NP_649699.1	Gem1	2..196	CDD:224025	98/193 (51%)
CG2656	NP_649699.1	ATP_bind_1	7..263	CDD:281079	122/255 (48%)
Y75B8A.14	NP_499587.1	Gem1	2..203	CDD:224025	102/211 (48%)
Y75B8A.14	NP_499587.1	ATP_bind_1	7..252	CDD:281079	122/255 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167776
Domainoid	1	1.000	257	1.000	Domainoid score	I1089
eggNOG	1	0.900	-	-		E1_KOG1534
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6487
Inparanoid	1	1.050	274	1.000	Inparanoid score	I1799
Isobase	1	0.950	-	0	Normalized mean entropy	S519
OMA	1	1.010	-	-		QHG53962
OrthoDB	1	1.010	-	-		D432496at33208
OrthoFinder	1	1.000	-	-		FOG0004799
OrthoInspector	1	1.000	-	-		oto18080
orthoMCL	1	0.900	-	-		OOG6_102080
Panther	1	1.100	-	-	LDO	PTHR21231
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R521
SonicParanoid	1	1.000	-	-		X3381
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	16.790