DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2656 and AgaP_AGAP001152

DIOPT Version :9

Sequence 1:	NP_649699.1	Gene:	CG2656 / 40857	FlyBaseID:	FBgn0037478	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	XP_322008.3	Gene:	AgaP_AGAP001152 / 1282014	VectorBaseID:	AGAP001152	Length:	297	Species:	Anopheles gambiae

Alignment Length:	290	Identity:	194/290 - (66%)
Similarity:	236/290 - (81%)	Gaps:	7/290 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRFAQIIVGPAGSGKSTYCSLMQQYAMDCKRNVQVVNLDPAAEHFTYNPLTDIRDLIHLDDAMED 65
            ||:.|:::|||||||||||:.||::..|.||.::|||||||||||.|.|..||||||.|||||||
Mosquito     1 MRYGQLVMGPAGSGKSTYCATMQRHGFDDKRMIKVVNLDPAAEHFDYQPFLDIRDLIQLDDAMED 65

  Fly    66 EELHYGPNGGLIFCLEFLIENQEWLKEQLCG-----GENELMVGEPDDDYILFDMPGQIELFTHL 125
            |||.||||||||||||:|||:.:||::||||     .::...:.||||||:||||||||||:|||
Mosquito    66 EELRYGPNGGLIFCLEYLIEHSDWLRDQLCGVGSDDEDDTTGIEEPDDDYVLFDMPGQIELYTHL 130

  Fly   126 KMGRQLVELLESWNFRTCVVFCLDSQFMVDGAKFISGTMAALSVMANMEQPHINVLTKVDLLSSD 190
            |.|..|..||||||||.|.||.:|||||:|||||:||||||||||||||.||:|||:|:||||..
Mosquito   131 KAGNSLARLLESWNFRLCSVFLVDSQFMIDGAKFLSGTMAALSVMANMELPHVNVLSKMDLLSKV 195

  Fly   191 ARKQLEMYLEPDAHSLMGELTIGTGFGEKYAKLTQAIGALIEDFSLVRFFPLDSQDEESVGDLLL 255
            .|.|::.||:||||:|:||:|..:.:|.||.||::.||.||||||||||.||:..|||:|.||||
Mosquito   196 HRGQMDKYLDPDAHALLGEVTNESAWGRKYRKLSETIGMLIEDFSLVRFTPLNINDEENVADLLL 260

  Fly   256 QIDSILQYGEDADVNVKDFD--EPEEGDQD 283
            .||:::||||||||.|:|||  ||||.:.|
Mosquito   261 MIDNVIQYGEDADVKVRDFDPPEPEEVEDD 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2656	NP_649699.1	Gem1	2..196	CDD:224025	137/198 (69%)
CG2656	NP_649699.1	ATP_bind_1	7..263	CDD:281079	174/260 (67%)
AgaP_AGAP001152	XP_322008.3	Gem1	6..193	CDD:224025	131/186 (70%)
AgaP_AGAP001152	XP_322008.3	ATP_bind_1	7..268	CDD:281079	174/260 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	370	1.000	Domainoid score	I2530
eggNOG	1	0.900	-	-		E1_KOG1534
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6487
Inparanoid	1	1.050	404	1.000	Inparanoid score	I3925
OMA	1	1.010	-	-		QHG53962
OrthoDB	1	1.010	-	-		D432496at33208
OrthoFinder	1	1.000	-	-		FOG0004799
OrthoInspector	1	1.000	-	-		oto110301
Panther	1	1.100	-	-	LDO	PTHR21231
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3381
TreeFam	1	0.960	-	-
	13	12.940