DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2656 and AgaP_AGAP004824

DIOPT Version :9

Sequence 1:	NP_649699.1	Gene:	CG2656 / 40857	FlyBaseID:	FBgn0037478	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	XP_317984.3	Gene:	AgaP_AGAP004824 / 1278404	VectorBaseID:	AGAP004824	Length:	871	Species:	Anopheles gambiae

Alignment Length:	245	Identity:	49/245 - (20%)
Similarity:	94/245 - (38%)	Gaps:	54/245 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 HLD-------DAMEDEELHYGPNGGLIFCLEFLIENQEWLKEQ--LCGGENELMVGEPDDDYILF 113
            |:|       |.:....:..|..||:...:.......|.:|||  ...|..||....|  ..::.
Mosquito   290 HVDTGKTKILDKLRRTNVQDGEAGGITQQIGATNVPSENIKEQTRFVKGFQELEFKLP--GLLII 352

  Fly   114 DMPGQIELFTHLK-MGRQLVELLESWNFRTCVVFCLDSQFMVDGAKFISGTMAALSVMANMEQPH 177
            |.||. |.|::|: .|..|.::         .:..:|   ::.|.:  ..|:.:::::.:...|.
Mosquito   353 DTPGH-ESFSNLRSRGSSLCDI---------AILVVD---IMHGLE--PQTIESINLLKSKRTPF 402

  Fly   178 INVLTKVDLL---SSDARKQLEMYLEPDAHSLMGELTIGTGFGEKYAKL-----TQAIGALI--- 231
            :..|.|:|.|   ::..||.:...|:..|.:...|      |.::..::     .|.:.|.:
Mosquito   403 VVALNKIDRLYDWNTMPRKDVRDILKAQASNTQLE------FNQRTKEIIVQFAEQGLNAALFYE 461

  Fly   232 --EDFSLVRFFPLDSQDEESVGDLLL--------QIDSILQYGEDADVNV 271
              :..:.|...|..:...|.:|::|.        |:...|.|.||....|
Mosquito   462 NPDPKTYVSLVPTSAITGEGMGNMLFLIVQFCQKQLAKRLMYSEDLQATV 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2656	NP_649699.1	Gem1	2..196	CDD:224025	32/150 (21%)
CG2656	NP_649699.1	ATP_bind_1	7..263	CDD:281079	45/235 (19%)
AgaP_AGAP004824	XP_317984.3	PRK04004	278..855	CDD:235195	49/245 (20%)
		IF2_eIF5B	284..495	CDD:206674	43/227 (19%)
		aeIF5B_II	507..616	CDD:293904	1/5 (20%)
		IF-2	617..720	CDD:288813
		IF2_aeIF5B_IV	743..837	CDD:293911
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910