Protein Alignment CG10098 and SCRN1

DIOPT Version :9

• Sequence 1: NP_649694.1
• Gene: CG10098 / 40851
• FlyBaseID: FBgn0037472
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_001138986.1
• Gene: SCRN1 / 9805
• HGNCID: 22192
• Length: 434
• Species: Homo sapiens
• Alignment Length: 422
• Identity: 110/422 - (26%)
• Similarity: 182/422 - (43%)
• Gaps: 90/422 - (21%)

  Fly     6 CFVVLPENCAEGTLIIGRNA---EDEKNVNVASEVCFYDATE-VLEGKTD-GGASAETGGDMLRV 65
            |||..|....:|.::.|:|:   .||     ..||.::.|.: ..|.|.: ...|.:.......:
Human    29 CFVAFPPRAKDGLVVFGKNSARPRDE-----VQEVVYFSAADHEPESKVECTYISIDQVPRTYAI 88

  Fly    66 ILQKPQPGLWGGDFGANERGVALGLTWAAGENEAKDSDSLLGTDIVRLTLAVAKDVDDAVDRIGA 130
            ::.:| ..|||.:.||||.||.:..........|.:.::|||.|:|||.|...:...:|:|.|.:
Human    89 MISRP-AWLWGAEMGANEHGVCIANEAINTREPAAEIEALLGMDLVRLGLERGETAKEALDVIVS 152

  Fly   131 LVASHGHDNSKLN-----------FIACDAAAAWLVSCSGKVWAAEKLEASFLRLPSGGLAVTTV 184
            |:..||...:...           ::..|...||::...||.|||||:... :|.....|::||.
Human   153 LLEEHGQGGNYFEDANSCHSFQSAYLIVDRDEAWVLETIGKYWAAEKVTEG-VRCICSQLSLTTK 216

  Fly   185 VNKSSEGLDDAASFAAAHD----------AEAQAPAVDW--CGPKPAGDGTYTQHDMFETLRSAS 237
            ::.....|   .|:|.:..          :|..:|..|.  ||   ||..:..:.:...|:::..
Human   217 MDAEHPEL---RSYAQSQGWWTGEGEFNFSEVFSPVEDHLDCG---AGKDSLEKQEESITVQTMM 275

  Fly   238 NASSSRAATVSV------LSVKGIS---------C-HWFTGTPNAAESVFKPFVFAPNPRISPLT 286
            |....:|:.|.:      .:..|:|         | |:|||||:.:.|:||||:|..:.::.|.|
Human   276 NTLRDKASGVCIDSEFFLTTASGVSVLPQNRSSPCIHYFTGTPDPSRSIFKPFIFVDDVKLVPKT 340

  Fly   287 Q---------------VQAEADLT-LLHKLHSQRKPAALE-------HLRS----LE---LSCVD 321
            |               .|.:.|.. .|:|.|...: |.:|       .|||    ||   |..::
Human   341 QSPCFGDDDPAKKEPRFQEKPDRRHELYKAHEWAR-AIIESDQEQGRKLRSTMLELEKQGLEAME 404

  Fly   322 ELNNYFSLQDHASDELDELLKDCVEAEVKFYR 353
            |:.......|.|  |:.:|..|||:.|:||::
Human   405 EILTSSEPLDPA--EVGDLFYDCVDTEIKFFK 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10098	NP_649694.1	Ntn_hydrolase	73..>169	CDD:294319	34/106 (32%)
SCRN1	NP_001138986.1	Ntn_hydrolase	38..>247	CDD:294319	54/218 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146833
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4690
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	110	1.000	Inparanoid score	I4889
Isobase	1	0.950	-	0	Normalized mean entropy	S7996
OMA	1	1.010	-	-		QHG47750
OrthoDB	1	1.010	-	-		D322959at2759
OrthoFinder	1	1.000	-	-		FOG0002049
OrthoInspector	1	1.000	-	-		otm41563
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12994
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.820