DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlp84B and crip2

DIOPT Version :9

Sequence 1:	NP_001303418.1	Gene:	Mlp84B / 40849	FlyBaseID:	FBgn0014863	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_998662.2	Gene:	crip2 / 554826	ZFINID:	ZDB-GENE-040426-2889	Length:	206	Species:	Danio rerio

Alignment Length:	214	Identity:	77/214 - (35%)
Similarity:	100/214 - (46%)	Gaps:	41/214 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 APKCPRCGKSVYAAEERLAGGYVFHKNCFKCGMCNKSLDSTNCTEHERELYC-KTCHGRKFGPKG 72
            |.|||:|.|:||.||:..:.|..:||.|.||..|:|:|.:....||:.:.|| |.|:...|||||
Zfish     2 ASKCPKCEKTVYFAEKVSSLGKDWHKFCLKCERCSKTLTAGGHAEHDGKPYCHKPCYAALFGPKG 66

  Fly    73 YGFGTGAGTLSMD---NGSQFLRENGDVPSVRNGARLEPRA-------IARAPEGEG-------- 119
            ...| |||:...:   |.|         |...||.. .|:|       .:|.|...|
Zfish    67 VNIG-GAGSYVYEAPTNTS---------PPPNNGDS-APKAQEKWVPVSSRPPSKAGSITTFSGE 120

  Fly   120 ---CPRCGGYVYAAEQMLARGRSWHKECFKCGTCKKGLDSILCCEAPDKNIYC-KGCYAKKFGPK 180
               ||||...||.||::.:.|:.||:.|.:|..|.|.|.:....| .|...|| |.|||..||||
Zfish   121 ANLCPRCSKKVYFAEKVTSLGKDWHRPCLRCERCSKTLAAGSHAE-HDGQPYCHKPCYAVLFGPK 184

  Fly   181 GYGYGQGGGALQSDCYAHD 199
            |...|..|.      |.:|
Zfish   185 GVNTGGVGS------YIYD 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlp84B	NP_001303418.1	LIM1_MLP84B_like	11..64	CDD:188788	23/53 (43%)
		LIM_CRP_like	120..173	CDD:188712	21/53 (40%)
		LIM_CRP_like	222..275	CDD:188712
		LIM_CRP_like	325..378	CDD:188712
		LIM_CRP_like	421..474	CDD:188712
crip2	NP_998662.2	LIM1_TLP	5..58	CDD:188860	22/52 (42%)
crip2	NP_998662.2	LIM_TLP_like	124..177	CDD:188785	21/53 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1214165at2759
OrthoFinder	1	1.000	-	-		FOG0000284
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X318
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820