Protein Alignment Ufl1 and ufl1

DIOPT Version :10

• Sequence 1: NP_649690.1
• Gene: Ufl1 / 40843
• FlyBaseID: FBgn0037467
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_956900.1
• Gene: ufl1 / 393578
• ZFINID: ZDB-GENE-040426-1163
• Length: 793
• Species: Danio rerio
• Alignment Length: 812
• Identity: 290/812 - (35%)
• Similarity: 468/812 - (57%)
• Gaps: 67/812 - (8%)

  Fly     1 MGSDWDEIKRLAADFQKAQLTSTLQKLSERNCVEIVTLLLEKQMLEVVFTNDGKEYITPDHLERE 65
            |.:||:||:|||||||:||...|:|:||||||:|||:.|:|.:.|:||.|.|||||:||..:.||
Zfish     1 MAADWEEIRRLAADFQRAQFAETVQRLSERNCIEIVSKLVEDKKLDVVHTLDGKEYVTPAQISRE 65

  Fly    66 IQDELYVNGGRANLVEVSKTLNVDLSRIELLAERISAENQSVHLVLGQLIDEDYISHIAQEINEK 130
            |:||||::.||.|:|::.|.:||||..:|..|..|:..::...|:|||||||.|:..:|:|:|:|
Zfish    66 IRDELYMHRGRINVVDLQKIINVDLVHVEGRANEIAKSDRGTQLILGQLIDEAYLDRLAEEVNDK 130

  Fly   131 LVQRGEVSISELASQFDLPSDFLQHDVVEKHLGKIIKGRQDASNPRVFFTQAYIQRCKAKIRGAL 195
            |.:.|:|:|:||...:|||.|||. :.:...||::|:|:.|..|..:.||||::.|.||.|.|..
Zfish   131 LQEAGQVNIAELCKTYDLPGDFLT-EALNARLGRVIQGQLDQYNRGMIFTQAFLSRHKACICGLF 194

  Fly   196 AAITRPINVAVILQKIGVQEKIFYSLLDEIAPAGQ-----VTSKQANSQYVPHIYAKTQADWVNS 255
            :.||||..:..:|...|.||.:.||:|:|:..:.:     |..:|..:.|:|.||:|.|:.||.|
Zfish   195 SGITRPTQINNLLNLYGFQENLVYSMLEELVNSARLKGSVVGGRQDKAIYIPDIYSKAQSTWVES 259

  Fly   256 FYKQNSFLEYDAIQKLGISDAKSYIRKQFPNEEFLYLKRVALGARLV---ELTVVTALNECSATK 317
            |.|||.:||::::.:|||.|..:||:|:|.:...|:||...:|..:|   |.:|..|:|  |||
Zfish   260 FLKQNGYLEFESLTRLGIPDPINYIKKRFKSSRLLFLKTACVGRTIVDQLEASVEEAIN--SAT- 321

  Fly   318 QYLDLTTILPSNLSEEDI----EEVFSTIMAQKHSNPSNFVYLDGIVFSQPYLAQLVQPCQALAE 378
             ::||..:|||.|||||:    .||..::..|     |:...|...|.|:.::|..:...:.|.:
Zfish   322 -WVDLQPMLPSILSEEDVGILLNEVLRSMNVQ-----SSARLLSTSVVSEKFIAGCIALFEDLMQ 380

  Fly   379 SQAKAAI-DGGVYQQYIVEKTLAQKGNVSTQELEDEGKVDKRDERRKKASSG----KAGGGAQGR 438
            .:|:..: :..|:  .|.|..:.|..  :..|.....|.||||||||||:.|    |:|||...|
Zfish   381 QKAQKEVKNNPVF--LITEDDVKQSS--ALLETSASSKKDKRDERRKKAAEGGGSVKSGGGGNAR 441

  Fly   439 ETKTKSTKKHQRGKAAAQFDSDDE-DDAQQGSRGGGGASKKAVKPLELV---KTADIVKLITASL 499
            |.:.:.|||    |...:.|||:| ..:.||....|.....:|:.:..|   |..|..:.:...|
Zfish   442 EIRIRKTKK----KGRKEEDSDEETTHSSQGRNKLGDVQFLSVEEIVEVLEEKVCDSSEEMLQEL 502

  Fly   500 EEEGLEHLSKSIASLYTNQFNQTALARAQELFEATPQTNRRQTHAAIQDRINTLLIDIRLYEKGL 564
            .|:....|||....:.|..|..|:.:.|        ..:|::....:|:.||.|..:|||:|||.
Zfish   503 AEQLQRPLSKMYQEVVTTAFLSTSSSGA--------GGSRKKNMKDLQEEINNLYNNIRLFEKGT 559

  Fly   565 KLFPQDTQTQLVKYLLKSLGNEICNELSLYVASECNLTVKNTNLNVDQRNKLAQECEAQYRAALL 629
            |||..:||..:.|::||::..::.|.|..:||:|...:..:..:..:.|.|:..:...:.|:.|:
Zfish   560 KLFSDETQATVAKHVLKTVCTDVTNVLLSFVAAEHMTSDSSAAMTSEIRLKILAKLSDEVRSPLM 624

  Fly   630 EQNKALN-KSIDDFELATETVLKTCSMIIKKVDKKKDRLLIADHKKKLQKQLLECNEPALLLHLA 693
            :.:.:|| |:|::|....||..:.|.:.:||.|||::|..::.|::.|.:||.:..:|||:|||.
Zfish   625 KLHNSLNGKAIEEFLSCLETSAEECGLFLKKGDKKRERQALSVHRQALCEQLRDAEDPALVLHLT 689

  Fly   694 ALILFTTITGSILHASGKFVSAILQHIRGSLNEDQNALLLRYHDLVLQVL---------QAIP-- 747
            :::||..:|..:|||.|:.|..|:..::..:.|||:.||.:|..||::.|         :.:|
Zfish   690 SVLLFQNVTHCMLHAPGRCVPHIIGFLQSKIPEDQHKLLSQYQSLVVKQLVVQGHGAEKKTVPPE 754

  Fly   748 ------DSNESKLANEHLQTMQNQVVE--LAQ 771
                  ||::::.....|.::...:.:  |||
Zfish   755 GAGGPADSDDTESLQRELHSLSRDIKDTVLAQ 786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ufl1	NP_649690.1	E3_UFM1_ligase	7..280	CDD:462874	127/277 (46%)
ufl1	NP_956900.1	Required for E3 UFM1-protein ligase activity. /evidence=ECO:0000250|UniProtKB:O94874	2..212		101/210 (48%)
		E3_UFM1_ligase	7..284	CDD:462874	127/277 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	405..472		29/70 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	745..793		7/42 (17%)