Protein Alignment ftz and Nkx2-8

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_001100202.1
• Gene: Nkx2-8 / 299061
• RGDID: 1310629
• Length: 234
• Species: Rattus norvegicus
• Alignment Length: 151
• Identity: 43/151 - (28%)
• Similarity: 61/151 - (40%)
• Gaps: 37/151 - (24%)

  Fly   249 SDCKDSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMKSKKDR 313
            ||.:..::.|..:::.||||||:.|...||::...|..:|..|.|:..|:||||||.|.|.|:.|
  Rat    76 SDAEKRRKRRVLFSKAQTLELERRFRQQRYLSAPEREQLARLLRLTPTQVKIWFQNHRYKLKRGR 140

  Fly   314 -------------------------------TLDSSPEHC---GAGYTAMLPPLEATSTATTGAP 344
                                           ..|.||  |   |.| ||.:|..:.:|...|..|
  Rat   141 APGVTESSDVTASADLHAAPGLLRRVVVPVLVHDRSP--CNGRGEG-TAAVPQDKCSSRLATACP 202

  Fly   345 SVPVPMYHHHQTTAAYPAYSH 365
            ......:........:|||.|
  Rat   203 VQGYTAFGPGSALGLFPAYQH 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787
		Homeodomain	255..311	CDD:459649	23/55 (42%)
		KLF1_2_4_N	<321..404	CDD:425360	13/48 (27%)
Nkx2-8	NP_001100202.1	Homeodomain	82..138	CDD:459649	23/55 (42%)