Protein Alignment ftz and Nkx2-4

DIOPT Version :10

• Sequence 1: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_075993.1
• Gene: Nkx2-4 / 228731
• MGIID: 97349
• Length: 354
• Species: Mus musculus
• Alignment Length: 331
• Identity: 67/331 - (20%)
• Similarity: 101/331 - (30%)
• Gaps: 123/331 - (37%)

  Fly   161 TPSASEDVDYLDVYSPQSQTQKLKNG--DFATP-------------PPTTPTS------------ 198
            :|..:......|:.||..:|.|...|  |.|.|             ||:.|:|
Mouse     4 SPKHTTPFSVSDILSPIEETYKKFGGVMDGAPPGLGAPLGAAAYRAPPSGPSSQAAAVAAGMQPP 68

  Fly   199 --------------------------LPPLEGISTPPQS--------------------PGEKSS 217
                                      :||  |:|..|.|                    .|.:..
Mouse    69 HAMAGHNAAAAAAAAAAAAAAAATYHMPP--GVSQFPHSAMGSYCNGGLGNMGELPAYTDGMRGG 131

  Fly   218 SAVSQEINHRIVTAP---------------NGAGDFNWSHIEETLAS-----DCKDSKRTRQTYT 262
            :|.:....:...|.|               |.||..:.:.|.:...|     .....::.|..::
Mouse   132 AAAAATGWYGANTDPRYSSISRFMGPSAGVNVAGMGSLTGIADAAKSLAPLHAAAPRRKRRVLFS 196

  Fly   263 RYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMKSK---KDRTLDSSPEHCGA 324
            :.|..|||:.|...:|::...|..:|:.:.|:..|:||||||.|.|.|   ||:......:..|.
Mouse   197 QAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQLQQEGGL 261

  Fly   325 GYTAMLPP------------------LEATSTATTG----APSVPVPMYHHHQTTAAYPAYSHSH 367
            |.....||                  .....|.|.|    .|..|.|.....:.:.:.||.   |
Mouse   262 GPPPPPPPPSPRRVAVPVLVKDGKPCQNGAGTPTPGQGGQQPQAPTPAPELEELSPSPPAL---H 323

  Fly   368 SHGYGL 373
            ..|.||
Mouse   324 GPGGGL 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz	NP_477498.1	FTZ	1..248	CDD:397787	28/174 (16%)
		Homeodomain	255..311	CDD:459649	20/58 (34%)
		KLF1_2_4_N	<321..404	CDD:425360	16/75 (21%)
Nkx2-4	NP_075993.1	Homeodomain	189..245	CDD:459649	19/55 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	245..329		16/86 (19%)