Protein Alignment Dfd and hoxa1a

DIOPT Version :10

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_571611.1
• Gene: hoxa1a / 58051
• ZFINID: ZDB-GENE-000823-5
• Length: 329
• Species: Danio rerio
• Alignment Length: 432
• Identity: 109/432 - (25%)
• Similarity: 144/432 - (33%)
• Gaps: 151/432 - (34%)

  Fly    64 SVGGGGAGGMTGHP-----HSMHPADMVSDYMAHHHNPHSHSHSHTHSLPHHHSNSAISGHHQAS 123
            |:.|||.||..|..     |..|.........|...|..|.......::   .|...|:...| .
Zfish     9 SISGGGDGGSGGSCSVRAFHGDHGLSTFQSSCAVRLNSCSGDERFMSNI---SSQDVINSQPQ-Q 69

  Fly   124 AGGYSS-NYANATPPSHP----HSHPHAHPHQSLGYYVHHAPEFISAG-AVHSDPTNGYGPAANV 182
            ||.|.| ...:.|..:||    .|....:.|.:|...|..:..|...| .|:|         .|:
Zfish    70 AGSYQSPGTLSITYSAHPSYGTQSFCTGYNHYALNQDVESSVSFPQCGPLVYS---------GNI 125

  Fly   183 PNT----SNGGGGGGSGAV-LGGGAVGGSANGYYGGYGGGYGTANGSVGSTHSQG--------HS 234
            .:|    .:...|..||.| |.|....|||.         ||.::.....|...|        |.
Zfish   126 SSTVVQHRHHRHGYSSGNVHLHGQFQYGSAT---------YGNSSDQANLTFVAGCSNPLSPLHV 181

  Fly   235 PHSQMMDLPLQCSSTEPPTNTALGLQELGLKLEKRIEEAVPAGQQLQELGMRLRCDDMGSENDDM 299
            ||......||                          .:.||.||..
Zfish   182 PHHDACCSPL--------------------------SDGVPTGQTF------------------- 201

  Fly   300 SEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPWMKKIHVAGVANGSYQPGM 364
               |.:.:.|:|.:.|.                                        .|.|..|.
Zfish   202 ---DWMKVKRNPPKTGK----------------------------------------AGEYGFGG 223

  Fly   365 EPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDNK--- 426
            :|...||.::..|:.|||||||:|:||||.||:|||.:|.|:|.|:||||||||||.||..|
Zfish   224 QPNTVRTNFSTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGL 288

  Fly   427 -----------LPNTKNVRKKTVDANGNPTPVAKKPTKRAAS 457
                       |..|::..:|:..|...|:|   .||..|.|
Zfish   289 LPKSLSEQKDGLEKTEDASEKSPSAPSTPSP---SPTVEAYS 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeodomain	367..423	CDD:459649	34/55 (62%)
hoxa1a	NP_571611.1	Antp-type hexapeptide	200..205		1/26 (4%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	208..227		7/58 (12%)
		Homeodomain	229..282	CDD:459649	34/52 (65%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	277..329		16/54 (30%)