Protein Alignment Dfd and NKX1-1

DIOPT Version :9

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001277008.1
• Gene: NKX1-1 / 54729
• HGNCID: 24975
• Length: 448
• Species: Homo sapiens
• Alignment Length: 356
• Identity: 79/356 - (22%)
• Similarity: 113/356 - (31%)
• Gaps: 151/356 - (42%)

  Fly   122 ASAGGYSSNYANATPPSHPHSHPHAHPHQSLGYYVHHAPEFISAGAVHSDPTNGYGPAANVPNTS 186
            |.|||..:  |.|.||                    :|.:...||...::.||||         |
Human   141 AGAGGVGA--AGAEPP--------------------NAGDPFKAGEAETNDTNGY---------S 174

  Fly   187 NGGGG-----------------------------GGSGAVLGGGAVGGSANGYYGGYGGGYGTAN 222
            :||||                             |...|..|||.:|...:|..|.     ...:
Human   175 SGGGGHSPSADSGDEVPDDEDDDEDEAPETEAARGAEEARGGGGGLGARGSGCQGA-----AETD 234

  Fly   223 GSVGSTHSQGHSPHSQMMDLPLQCSSTEPPTNTALGLQELGLKLEKRIEEAVPAGQQLQELGMRL 287
            .|.|:|..:..:|                           |.:....:.:..|.|.
Human   235 ASPGATVDEAAAP---------------------------GPRENSPVAQGPPGGA--------- 263

  Fly   288 RCDDMGSENDDMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPWMKKIHV 352
                                 .:|...|:...    |.:.:.:              |..|:
Human   264 ---------------------AAPGGAGTTPQ----GTATAAK--------------PKRKR--- 286

  Fly   353 AGVANGSYQPGMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNR 417
                .||.....:|:|.|||:|..|::.||.:|...|||:...|:.:|.:|.|:|.|:|||||||
Human   287 ----TGSDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNR 347

  Fly   418 RMKWKKDNKLPNTKNVRKKTVDANGNPTPVA 448
            |.||||.|...:|    .......|.|.|.|
Human   348 RTKWKKQNPGADT----SAPTGGGGGPGPGA 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	26/51 (51%)
NKX1-1	NP_001277008.1	Homeobox	300..352	CDD:278475	26/51 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910