Protein Alignment Dfd and HOXA9

DIOPT Version :10

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_689952.1
• Gene: HOXA9 / 3205
• HGNCID: 5109
• Length: 272
• Species: Homo sapiens
• Alignment Length: 338
• Identity: 89/338 - (26%)
• Similarity: 119/338 - (35%)
• Gaps: 132/338 - (39%)

  Fly   106 SLPHHHSNSAISGHHQASAGGYSSN-----YANATPPS---HPHSHPHAHPHQSLGYYVHHAPEF 162
            :|..|...|..|...:|:..|.|.|     .|||.|.:   |.|.||:.||         .||
Human    44 TLAEHPDFSPCSFQSKATVFGASWNPVHAAGANAVPAAVYHHHHHHPYVHP---------QAP-- 97

  Fly   163 ISAGAVHS-------DPTNGYGPAANVPNTSNGGGGGGSGAVLGGGAVGGSANGYYGGYGGGYGT 220
            ::|.|...       :||.|....|.:|
Human    98 VAAAAPDGRYMRSWLEPTPGALSFAGLP------------------------------------- 125

  Fly   221 ANGSVGSTHSQGHSPHSQMMDLPLQCSSTEPPTNTALGLQELGLKLEKRIEEAVPAGQQLQELGM 285
                  |:...|..|.      ||.....:.||     |....|.|......:.|..::.|.
Human   126 ------SSRPYGIKPE------PLSARRGDCPT-----LDTHTLSLTDYACGSPPVDREKQP--- 170

  Fly   286 RLRCDDMGSENDDMSEE--DRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPWMK 348
               .:...|||:..:|.  |:..:|  |:...:|                            |
Human   171 ---SEGAFSENNAENESGGDKPPID--PNNPAAN----------------------------W-- 200

  Fly   349 KIHVAGVANGSYQPGMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIW 413
             :|....           :::|..||:||.|||||||.:|.||||.||.|:|..|.|:|||:|||
Human   201 -LHARST-----------RKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIW 253

  Fly   414 FQNRRMKWKKDNK 426
            |||||||.||.||
Human   254 FQNRRMKMKKINK 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeodomain	367..423	CDD:459649	36/55 (65%)
HOXA9	NP_689952.1	Hox9_act	1..193	CDD:461369	45/221 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	155..198		9/50 (18%)
		Homeodomain	207..263	CDD:459649	36/55 (65%)