Protein Alignment Dfd and HOXA5

DIOPT Version :10

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_061975.2
• Gene: HOXA5 / 3202
• HGNCID: 5106
• Length: 270
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 103/318 - (32%)
• Similarity: 134/318 - (42%)
• Gaps: 81/318 - (25%)

  Fly   128 SSNYANATPPSHPHSHPHAHPHQSLGYYVHH---APEFISAGAVHSDPTNGYGPAANVPNTSNGG 189
            ||.:.|:....:|:.     |...|..|..|   :.:|..:.::||   ..||...|..:.|
Human     2 SSYFVNSFCGRYPNG-----PDYQLHNYGDHSSVSEQFRDSASMHS---GRYGYGYNGMDLS--- 55

  Fly   190 GGGGSGAVLGGGAVGGSANGYYG-GYGGGYGTANGSVGSTHSQGHSP----HSQMMDLPLQCSST 249
                         ||.|.:|::| |.......|:.|......:...|    ||...| ||.||:.
Human    56 -------------VGRSGSGHFGSGERARSYAASASAAPAEPRYSQPATSTHSPQPD-PLPCSAV 106

  Fly   250 EPPTNTALGLQELGLKLEKRIEEAVPAGQQLQELGMRLRCDDMGSENDDMSEEDRLMLDRSPDEL 314
            .|...:                                  |......:.:|.......|.....:
Human   107 APSPGS----------------------------------DSHHGGKNSLSNSSGASADAGSTHI 137

  Fly   315 GSNDNDDDLGDSDSDEDLMAETTDGER----------IIYPWMKKIHVAGVANGSYQPGMEPKRQ 369
            .|.:.......::.|....:|....:.          .|||||:|:|::....|    |.|.||.
Human   138 SSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQIYPWMRKLHISHDNIG----GPEGKRA 198

  Fly   370 RTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDNKL 427
            ||||||:|.||||||||:||||||||||||||.|.|||||||||||||||||||||||
Human   199 RTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKL 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeodomain	367..423	CDD:459649	49/55 (89%)
HOXA5	NP_061975.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..175		17/134 (13%)
		Antp-type hexapeptide	176..181		4/4 (100%)
		Homeodomain	196..252	CDD:459649	49/55 (89%)