Protein Alignment Dfd and TLX1

DIOPT Version :9

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: XP_011538046.1
• Gene: TLX1 / 3195
• HGNCID: 5056
• Length: 342
• Species: Homo sapiens
• Alignment Length: 431
• Identity: 98/431 - (22%)
• Similarity: 142/431 - (32%)
• Gaps: 160/431 - (37%)

  Fly   140 PHSHPHAHPHQSLGYYVHHAPEFISAGAVHSDPTNG--YGPAANVPNTSNG----------GGGG 192
            ||   |.||.       |..|.......:.:.|..|  .|||:.:.:...|          .|||
Human     6 PH---HLHPG-------HAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGG 60

  Fly   193 GSGAVLGGGAVGGSANGYYGGYG------------------------------GGYGTANGSVGS 227
            ||.|..|.|..|....|..||.|                              ||.|.::|..|:
Human    61 GSAAATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGSSGGAGA 125

  Fly   228 THSQG------HSPHSQMMDLPLQCSSTEPPTNTALGLQELGLKLEKRIEEAVPAGQQLQEL-GM 285
            ..:.|      |.|         ...:...|...|.||..:         .:|||...:..| |:
Human   126 LSAAGVIRVPAHRP---------LAGAVAHPQPLATGLPTV---------PSVPAMPGVNNLTGL 172

  Fly   286 RLRCDDMGSENDDMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPWMKKI 350
            ..    ...|::....:||..:..||                        .|...||.:|
Human   173 TF----PWMESNRRYTKDRFTVALSP------------------------FTVTRRIGHP----- 204

  Fly   351 HVAGVANGSYQPGMEPKRQ--RTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIW 413
                     ||....||::  ||::||.||.||||.||..:||....|..:|..|.:::.|:|.|
Human   205 ---------YQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTW 260

  Fly   414 FQNRRMKWKKDNKLPNTKNVRKKTVDANGNPTPVAKKPTKRAASKKQQQAQ------QQQQSQQQ 472
            |||||.||::.                           |......::|||.      ||:..|:.
Human   261 FQNRRTKWRRQ---------------------------TAEEREAERQQANRILLQLQQEAFQKS 298

  Fly   473 QTQQTPVMNECIRSDSLESIGDVSSSLGNPPYIPAAPETTS 513
            ..|..|....|:.:.||.::.::.      |:...:.:.||
Human   299 LAQPLPADPLCVHNSSLFALQNLQ------PWSDDSTKITS 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	26/51 (51%)
TLX1	XP_011538046.1	Homeobox	216..269	CDD:278475	26/52 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910