DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dfd and DBX1

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_001025036.2	Gene:	DBX1 / 120237	HGNCID:	33185	Length:	343	Species:	Homo sapiens

Alignment Length:	207	Identity:	49/207 - (23%)
Similarity:	86/207 - (41%)	Gaps:	49/207 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   358 GSYQPGM--------------------------EPKR---QRTAYTRHQILELEKEFHYNRYLTR 393
            ||:||.:                          :|:|   :|..::..|...|||.|...:|:::
Human   144 GSFQPFIRSSYFPASSSVVPIPGTFSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISK 208

  Fly   394 RRRIEIAHTLVLSERQIKIWFQNRRMKWK--KDNKLPNTKNVRKKTVDANGNPTPVAKKPTKRAA 456
            ..|.::|..|.|.:.|:|||||||||||:  |:.:|.::...|::|:....||.|......::..
Human   209 PDRKKLAAKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSDVGQKGP 273

  Fly   457 SKKQQQAQQQQQSQQ--QQTQQTPVMNECIRSDSLESIGDVSSSLGNPPYIPAAPETTSSYPGSQ 519
            ..::::......|.:  ......|   :.:|...|            |..:|.:|..:|| ||..
Human   274 GNEEEEEGPGSPSHRLAYHASSDP---QHLRDPRL------------PGPLPPSPAHSSS-PGKP 322

  Fly   520 QHLSNNNNNGSG 531
            ...|::.....|
Human   323 SDFSDSEEEEEG 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	22/51 (43%)
DBX1	NP_001025036.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	56..100
		Homeobox	184..237	CDD:278475	22/52 (42%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	240..343		20/111 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910