Protein Alignment bcd and Pdx1

DIOPT Version :10

• Sequence 1: NP_788587.1
• Gene: bcd / 40830
• FlyBaseID: FBgn0000166
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_032840.1
• Gene: Pdx1 / 18609
• MGIID: 102851
• Length: 284
• Species: Mus musculus
• Alignment Length: 275
• Identity: 66/275 - (24%)
• Similarity: 103/275 - (37%)
• Gaps: 99/275 - (36%)

  Fly    10 FYHHPLPHTHTHPHPHSHPHPHSHPHPHHQHPQLQLPPQFR--------------NPFD---LLF 57
            |...|:|....:|....:......|.|         ||||.              :|::   |..
Mouse    20 FQRGPVPEFSANPPACLYMGRQPPPPP---------PPQFTSSLGSLEQGSPPDISPYEVPPLAS 75

  Fly    58 DERTGAINYNYIRPYLPNQM----PKPDVFPSE------ELPDSLVMRRP--------------- 97
            |:..||    ::..:||.|:    |.|..||:.      |.|:.:.:..|
Mouse    76 DDPAGA----HLHHHLPAQLGLAHPPPGPFPNGTEPGGLEEPNRVQLPFPWMKSTKAHAWKGQWA 136

  Fly    98 -----------RRTRTTFTSSQIAELEQHFLQGRYLTAPRLADLSAKLALGTAQVKIWFKNRRRR 151
                       :||||.:|.:|:.|||:.||..:|::.||..:|:..|.|....:||||:|||.:
Mouse   137 GGAYTAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMK 201

  Fly   152 HKIQSDQHKDQSYEGMPLSPGMKQSDGDPP-------------SLQTLSLGGGAT---------- 193
            .|.:.|:.:.   .|.|...|    .|:.|             ::..|...|||.
Mouse   202 WKKEEDKKRS---SGTPSGGG----GGEEPEQDCAVTSGEELLAVPPLPPPGGAVPPGVPAAVRE 259

  Fly   194 ---PNALTPSPTPST 205
               |:.|:.||.||:
Mouse   260 GLLPSGLSVSPQPSS 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bcd	NP_788587.1	Homeodomain	106..153	CDD:459649	19/46 (41%)
Pdx1	NP_032840.1	Transactivation domain. /evidence=ECO:0000250	13..73		11/61 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..116		21/98 (21%)
		Antp-type hexapeptide	119..124		1/4 (25%)
		Homeodomain	148..204	CDD:459649	24/55 (44%)
		Nuclear localization signal	198..204		2/5 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	202..284		17/80 (21%)