Protein Alignment zen and HOXA3

DIOPT Version :10

• Sequence 1: NP_476793.1
• Gene: zen / 40828
• FlyBaseID: FBgn0004053
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_109377.1
• Gene: HOXA3 / 3200
• HGNCID: 5104
• Length: 443
• Species: Homo sapiens
• Alignment Length: 139
• Identity: 59/139 - (42%)
• Similarity: 72/139 - (51%)
• Gaps: 35/139 - (25%)

  Fly    40 PIGLPPNYNQMNSNPTTLNDHCSP-------------------QHVHQQHVSS--------DENL 77
            |....|..|..| |||..|...||                   |:..|:..||        |::.
Human   122 PSSASPPQNASN-NPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGESCAGDKSP 185

  Fly    78 PSQPNHDSQRVKLKRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQVKIWFQNRR 142
            |.|.:.       ||:|||:||.||||||.||..|.||.|.||:|:|..|:|.|||:||||||||
Human   186 PGQASS-------KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRR 243

  Fly   143 MKFKKDIQG 151
            ||:|||.:|
Human   244 MKYKKDQKG 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeodomain	91..147	CDD:459649	38/55 (69%)
HOXA3	NP_109377.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..147		10/25 (40%)
		Antp-type hexapeptide	155..160		0/4 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	159..196		9/43 (21%)
		Homeodomain	192..248	CDD:459649	38/55 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	247..338		4/6 (67%)
		DUF4074	377..441	CDD:463833
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	400..443