Protein Alignment zen and Hoxb2

DIOPT Version :10

• Sequence 1: NP_476793.1
• Gene: zen / 40828
• FlyBaseID: FBgn0004053
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_598793.2
• Gene: Hoxb2 / 103889
• MGIID: 96183
• Length: 354
• Species: Mus musculus
• Alignment Length: 322
• Identity: 85/322 - (26%)
• Similarity: 125/322 - (38%)
• Gaps: 61/322 - (18%)

  Fly    40 PIGLP-PNYNQMNSNPTT---LNDHCSP----QHVHQQHVSSDENLPSQPNHDSQRVKLKRSRTA 96
            |:..| |.:..|....:|   .....||    ..|....|.|..:.|..|.....  ..:|.|||
Mouse    85 PVAPPAPEFPWMKEKKSTKKPSQSAASPSPAASSVRASEVGSPSDGPGLPECGGS--GSRRLRTA 147

  Fly    97 FTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQVKIWFQNRRMKFKKDIQGHREPKSNAKL 161
            :|:.||:|||.||..|.||.|.||:|||..|.|.|||||:||||||||.|:..| ||||
Mouse   148 YTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ-HREP------ 205

  Fly   162 AQPQAEQSAHRGIVKRLMSYSQDPREGTAAAEKRPMMAVAPVNPKPDYQASQKMKTEASTNNGMC 226
              |:.|                                  |..|.....|.:..: |.:.:.|..
Mouse   206 --PEGE----------------------------------PGGPSAQDDAGEPAE-EPTVSPGDV 233

  Fly   227 SSADLSEILEHLAQTTAAPQVSTATSSTGTSTNSASSSSSGHYSYNVDLVLQSIKQDLEAAAQAW 291
            ::..|.|...|.|:....|:.:..::...|:..|..:||.|     ..::....:|.......|.
Mouse   234 ATHRLREACFHPAEAAQGPRGAPPSALPATTLESVGASSPG-----CTMLRAGGRQSEPLPEDAC 293

  Fly   292 SKSKSAPILATQSWHPSSQSQVPTSVHAAPSMNLSWGEPAAKS-RKLSVNHMNPCVTSYNYP 352
            .:.:.:|.|...::. ::.|.:..|...:||:..|...|...| .:|.......|.....:|
Mouse   294 PERQDSPFLPDLNFF-AADSCLQMSGGLSPSLQGSLDSPVPFSEEELDFFTSTLCAIDLQFP 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeodomain	91..147	CDD:459649	36/55 (65%)
Hoxb2	NP_598793.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	39..143		12/59 (20%)
		Antp-type hexapeptide	92..97		0/4 (0%)
		Homeodomain	142..198	CDD:459649	36/55 (65%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	193..231		15/81 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	246..295		9/53 (17%)