Protein Alignment zen2 and NKX2-8

DIOPT Version :10

• Sequence 1: NP_476794.1
• Gene: zen2 / 40827
• FlyBaseID: FBgn0004054
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_055175.2
• Gene: NKX2-8 / 26257
• HGNCID: 16364
• Length: 239
• Species: Homo sapiens
• Alignment Length: 133
• Identity: 49/133 - (36%)
• Similarity: 62/133 - (46%)
• Gaps: 28/133 - (21%)

  Fly    31 AAPTATTRSSEKSKRSRTAFSSLQLIELEREFHLNKYLARTRRIEISQRLALTERQVKIWFQNRR 95
            |.|.:....:||.|:.|..||..|.:||||.|...:||:...|.:::..|.||..||||||||.|
Human    72 ARPASPGSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHR 136

  Fly    96 MKLKKSTNRKGAIGALTTSIPLSSQSSEDLQKDDQIVERLLRYANTNVETAP--LRQVDHGVL-E 157
            .|||    |..|.||         ..|.||.            |:..:..||  ||:|...|| .
Human   137 YKLK----RARAPGA---------AESPDLA------------ASAELHAAPGLLRRVVVPVLVR 176

  Fly   158 EGQ 160
            :||
Human   177 DGQ 179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen2	NP_476794.1	Homeodomain	44..100	CDD:459649	27/55 (49%)
NKX2-8	NP_055175.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..87		5/14 (36%)
		Homeodomain	85..141	CDD:459649	28/59 (47%)