Protein Alignment zen2 and NKX2-3

DIOPT Version :10

• Sequence 1: NP_476794.1
• Gene: zen2 / 40827
• FlyBaseID: FBgn0004054
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_660328.2
• Gene: NKX2-3 / 159296
• HGNCID: 7836
• Length: 364
• Species: Homo sapiens
• Alignment Length: 164
• Identity: 48/164 - (29%)
• Similarity: 69/164 - (42%)
• Gaps: 39/164 - (23%)

  Fly    32 APTATTRSSEKSKRS-RTAFSSLQLIELEREFHLNKYLARTRRIEISQRLALTERQVKIWFQNRR 95
            |...:.|...:|:|. |..||..|:.||||.|...:||:...|..::..|.||..||||||||||
Human   136 AAEESERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRR 200

  Fly    96 MKLKKSTNRKGAIGALTTSIPLSSQSSEDLQKDDQIVERLLRYANTNVETAPLRQVDHGVL-EEG 159
            .|.|:                         |:.|:.:|     ...:....|.|:|...|| .:|
Human   201 YKCKR-------------------------QRQDKSLE-----LGAHAPPPPPRRVAVPVLVRDG 235

  Fly   160 Q--ITPPYQSYDYLHEFSPEPMALPQLPFNEFDA 191
            :  :||..|:|.     :|..:......:|.|.|
Human   236 KPCVTPSAQAYG-----APYSVGASAYSYNSFPA 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen2	NP_476794.1	Homeodomain	44..100	CDD:459649	27/56 (48%)
NKX2-3	NP_660328.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	132..153		4/16 (25%)
		Homeodomain	149..205	CDD:459649	27/55 (49%)