Protein Alignment pb and Hoxa5

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_077365.1
• Gene: Hoxa5 / 79241
• RGDID: 620609
• Length: 381
• Species: Rattus norvegicus
• Alignment Length: 254
• Identity: 81/254 - (31%)
• Similarity: 107/254 - (42%)
• Gaps: 80/254 - (31%)

  Fly    48 GVGGVGVSVGQPGIGQQGVPPVPSVLMVNKMTPNCDKRSADTAYWMTASEGGFINSQPSMAEFLN 112
            |..|:.:|||:.|.|..|                ..:|:...|...:|:......|||:.:   .
  Rat   159 GYNGMDLSVGRSGSGHFG----------------SGERARSYAAGASAAPAEPRYSQPATS---T 204

  Fly   113 HLSPESP--------------------KIGTPVGSGAIGGVGVNVNVNVGVGVGYPVGVVPQTP- 156
            |..|..|                    .:|...|:.|..|   :.:::...|||.........|
  Rat   205 HSPPPDPLPCSAVAPSPGSDSHHGGKNSLGNSSGASANAG---STHISSREGVGTASAAEEDAPA 266

  Fly   157 ----DGMDSVPE---------YPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNT 208
                .|..|.|.         ||||::...|     ::|.|.       ||.   :|.|||||..
  Rat   267 SSEQAGAQSEPSPAPPAQPQIYPWMRKLHIS-----HDNIGG-------PEG---KRARTAYTRY 316

  Fly   209 QLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNK 267
            |.||||||||||:||.|.||||||.:|.|:|||:|:||||||||.|:         |||
  Rat   317 QTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK---------DNK 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	40/55 (73%)
Hoxa5	NP_077365.1	Homeodomain	307..363	CDD:459649	40/55 (73%)