Protein Alignment pb and alx1

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_001038539.1
• Gene: alx1 / 565176
• ZFINID: ZDB-GENE-050419-191
• Length: 320
• Species: Danio rerio
• Alignment Length: 269
• Identity: 70/269 - (26%)
• Similarity: 100/269 - (37%)
• Gaps: 67/269 - (24%)

  Fly   151 VVPQT--PDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLEL 213
            |.|.|  ||..| :.|   :.||..|..||:..                 ||.||.:|:.||.||
Zfish    92 VSPATSGPDKTD-LDE---LGEKCDSNVSSSKK-----------------RRHRTTFTSAQLEEL 135

  Fly   214 EKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMK-HKRQTLSKTDDEDNK-------DSL 270
            ||.|....|.....|.::|...:|||.:|:|||||||.| .||:...:.....:.       ..|
Zfish   136 EKVFQKTHYPDVYVREQLAMRTELTEARVQVWFQNRRAKWRKRERYGQIQQAKSHFAATYDISML 200

  Fly   271 KGDDDQSDSNSN-------SKKSCQGCELPSDDIPDSTSNSRGHNNNTPSATNNNPSAGNLT--- 325
            ...|..|..::|       .......|.:|           ||   :.|..|:..|.:....
Zfish   201 PRTDSYSQISNNLWTGPSAGSSVVSSCMIP-----------RG---SPPCVTSPYPHSPRAAEHG 251

  Fly   326 ----PNSSLETGISSNLMGSTTVSASNVISADSSVASSVSLDEDIEESSPIKVKKKDDGQVIKKE 386
                ||.      ..|..|...||.:|.. |||.:|||.: .....|:.|...::.....|::.:
Zfish   252 YVGFPNH------QQNQFGVNHVSLNNFF-ADSLLASSAN-SHAAFETKPEFERRSSSIAVLRMK 308

  Fly   387 AVSTSSKAS 395
            |...::..|
Zfish   309 AKEHTANIS 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	27/56 (48%)
alx1	NP_001038539.1	Homeodomain	121..177	CDD:459649	27/55 (49%)
		Transactivation domain. /evidence=ECO:0000250|UniProtKB:Q63087	180..320		29/160 (18%)
		OAR	296..314	CDD:461067	2/17 (12%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	300..313		2/12 (17%)