Protein Alignment pb and nkx2.7

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_571494.1
• Gene: nkx2.7 / 30694
• ZFINID: ZDB-GENE-990415-179
• Length: 269
• Species: Danio rerio
• Alignment Length: 300
• Identity: 76/300 - (25%)
• Similarity: 110/300 - (36%)
• Gaps: 84/300 - (28%)

  Fly    60 GIGQQGVPPVPSVLMVNKMTPNCDKRSADTAYWMTASEGGFINSQPSMAEFLNHLSPESPKIGTP 124
            |:.|..| |:.|:.:  :...|...||.|..|                          ||:.|.|
Zfish    32 GVEQDSV-PLQSLQL--QCMQNTLSRSLDLLY--------------------------SPEKGIP 67

  Fly   125 VGSGAIGGVGVNVNVN----VGVGVGYPVGVVPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGD 185
                     |..|..:    |....|.|      |.:.||:..|........:|..|.|.....:
Zfish    68 ---------GEQVKCDDFDIVRSSCGSP------TEEEMDANEETSMCPFTDSSYSSKNGETLRE 117

  Fly   186 NSITEFVPENGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRR 250
            .      |:..|.|:.|..::.||:.|||:.|...:||..|.|..:|.:|.||..|||:||||||
Zfish   118 K------PKQRLRRKPRVLFSQTQVFELERRFKQQRYLSAPERDHLALALKLTSTQVKIWFQNRR 176

  Fly   251 MKHKRQTLSKTDDEDNKDSLKGDDDQS------DSNSNSKKSCQGC------ELPSDDIPDSTSN 303
            .|.|||.      :|....|.|....:      |.     |.|.|.      ..|.::..:|..|
Zfish   177 YKCKRQR------QDKSLELAGPRRVAVPVLVRDG-----KPCHGAPYNVTVSYPYNNYYNSYGN 230

  Fly   304 SRGHNNNT--PSATNNNPSAGNLTPNSSLETGISSNLMGS 341
            :..|.|.|  ||..|.:.     .||..::..:::..:.|
Zfish   231 NPYHCNFTSVPSFANTSQ-----IPNHFVDMNLTTGSVDS 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	26/55 (47%)
nkx2.7	NP_571494.1	COG5576	87..210	CDD:227863	44/139 (32%)
		Homeodomain	125..181	CDD:459649	26/55 (47%)