Protein Alignment pb and ALX3

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_006483.2
• Gene: ALX3 / 257
• HGNCID: 449
• Length: 343
• Species: Homo sapiens
• Alignment Length: 370
• Identity: 87/370 - (23%)
• Similarity: 128/370 - (34%)
• Gaps: 83/370 - (22%)

  Fly    46 VGGVGGVGVSVGQPGIGQQGVP-------PVP-------SVLMVNKMTPNCDKRSADTAYWM--- 93
            ||...|..|:.|....|.||.|       |.|       .......:.|...:.:...|.::
Human    11 VGPAPGPYVASGDEPPGPQGTPAAAPHLHPAPPRGPRLTRFPACGPLEPYLPEPAKPPAKYLQDL 75

  Fly    94 ---TASEGGFINSQPSMAEFLNHLSPESPKIGTPVGSGAIGGVGVNVNVNVG---VGVGYPVGVV 152
               .|..||.....|:.||.....:...|::......|...|.. |:..:.|   ..:..|:.
Human    76 GPGPALNGGHFYEGPAEAEEKTSKAASFPQLPLDCRGGPRDGPS-NLQGSPGPCLASLHLPLS-- 137

  Fly   153 PQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEKEF 217
            |..||.|:..        |..|:|                      ||.||.::..||.||||.|
Human   138 PGLPDSMELA--------KNKSKK----------------------RRNRTTFSTFQLEELEKVF 172

  Fly   218 HFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMK-HKRQTLSKTDDEDNKDSLKGDDD---QSD 278
            ....|.....|.::|...||||.:|:|||||||.| .||:...|..:..|..:...|..   ::|
Human   173 QKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKIQEGRNPFTAAYDISVLPRTD 237

  Fly   279 SN---SNSKKSCQG-------CELPSDDIPDSTSNSRGHNNNTPSATNNNPSAGNLTPNSSLETG 333
            |:   .||..:..|       |.:..:.||....:...|.:.:.:.....|:.....|......|
Human   238 SHPQLQNSLWASPGSGSPGGPCLVSPEGIPSPCMSPYSHPHGSVAGFMGVPAPSAAHPGIYSIHG 302

  Fly   334 ISSNLMGSTTVSASNVISADSSVASSVSLDEDIEESSPIKVKKKD 378
            ....|.|.:...:|:   .|....|.|||          :||.|:
Human   303 FPPTLGGHSFEPSSD---GDYKSPSLVSL----------RVKPKE 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	27/56 (48%)
ALX3	NP_006483.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..104		19/92 (21%)
		PRK12323	<13..131	CDD:481241	22/118 (19%)
		Homeodomain	154..210	CDD:459649	27/55 (49%)