Protein Alignment pb and DLX5

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_005212.1
• Gene: DLX5 / 1749
• HGNCID: 2918
• Length: 289
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 74/274 - (27%)
• Similarity: 119/274 - (43%)
• Gaps: 67/274 - (24%)

  Fly   104 QPSMAEFLNHLSPESPKI---------------GTPVG----SGAIGGVGVN--------VNVNV 141
            |.|.|  ::|.|.|||.:               |.|.|    :.|..|..:|        ||.:.
Human    22 QTSAA--MHHPSQESPTLPESSATDSDYYSPTGGAPHGYCSPTSASYGKALNPYQYQYHGVNGSA 84

  Fly   142 GVGVGYPVGVVPQTPDGMDSVPEYPWMKEKKTSRKSSNN----NNQGDNSITEFVPE----NGLP 198
            |   .||.          .:..:|.:.........:.|.    .||.:..:||  ||    ||.|
Human    85 G---SYPA----------KAYADYSYASSYHQYGGAYNRVPSATNQPEKEVTE--PEVRMVNGKP 134

  Fly   199 RRL---RTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSK 260
            :::   ||.|::.||..|::.|...:||..|.|.|:||||.||:.|||:||||:|.|.|:  :.|
Human   135 KKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNKRSKIKK--IMK 197

  Fly   261 TDDEDNKDSLKGDDDQSDSNSNSKKSCQGCELPSDDIPDSTSNSRGHNNNT-PSATNNNPSAGNL 324
            ..:...:.|         .:|:...:|...:.|:...|..:|.|..|:.:. |..:|.:|::..|
Human   198 NGEMPPEHS---------PSSSDPMACNSPQSPAVWEPQGSSRSLSHHPHAHPPTSNQSPASSYL 253

  Fly   325 TPNSSLETGISSNL 338
            ..::|..|..:|::
Human   254 ENSASWYTSAASSI 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	27/58 (47%)
DLX5	NP_005212.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..49		8/28 (29%)
		DLL_N	32..118	CDD:463567	17/98 (17%)
		Homeodomain	138..194	CDD:459649	27/55 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	198..251		11/61 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	270..289