Protein Alignment pb and DLX4

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_612138.1
• Gene: DLX4 / 1748
• HGNCID: 2917
• Length: 240
• Species: Homo sapiens
• Alignment Length: 215
• Identity: 55/215 - (25%)
• Similarity: 85/215 - (39%)
• Gaps: 67/215 - (31%)

  Fly   143 VGVGYPVGVVPQT---PDGMDSVP-----EYPWMKEKKTSRKSSNNNNQGDNSIT---------- 189
            |...||:|:.|.|   |:...|.|     .||:.:..          |.||:.::
Human    27 VAAAYPLGLSPTTAASPNLSYSRPYGHLLSYPYTEPA----------NPGDSYLSCQQPAALSQP 81

  Fly   190 ---------EFVPENGLP------------------RRLRTAYTNTQLLELEKEFHFNKYLCRPR 227
                     |...::..|                  |:.||.|::.||..|.:.|...:||..|.
Human    82 LCGPAEHPQELEADSEKPRLSPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPE 146

  Fly   228 RIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSDSNSNSKKSCQGCEL 292
            |.::||.|.||:.|||:||||:|.|:|:..         |.:..|.:......:.|...|.. .|
Human   147 RAQLAAQLGLTQTQVKIWFQNKRSKYKKLL---------KQNSGGQEGDFPGRTFSVSPCSP-PL 201

  Fly   293 PS-DDIPDS-TSNSRGHNNN 310
            || .|:|.: |..:.|:.|:
Human   202 PSLWDLPKAGTLPTSGYGNS 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	26/55 (47%)
DLX4	NP_612138.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	80..120		3/39 (8%)
		Homeodomain	118..174	CDD:459649	26/55 (47%)