Protein Alignment pb and Hlx

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_032276.1
• Gene: Hlx / 15284
• MGIID: 96109
• Length: 476
• Species: Mus musculus
• Alignment Length: 422
• Identity: 98/422 - (23%)
• Similarity: 150/422 - (35%)
• Gaps: 118/422 - (27%)

  Fly    56 VGQPGIGQQGVPPVPSVLM--VNKMTPNCDKRSADTAYW-----MTASE--GGFINS-QPSMAEF 110
            ||:||...:|:....:.|.  :..:.|:...::|..:..     :..||  .||... .|..|.|
Mouse    54 VGEPGPAAEGLVGASAALTAHLGSVHPHASFQAAARSPLRPTPVVAPSEVPAGFPQRLSPLSAAF 118

  Fly   111 LNHLSPES----------------------PKIGTPVGSGAIGGVGVNVNVNVGVGV-------- 145
            ..||..:|                      |..||.|.....|......:.::..|:
Mouse   119 HQHLPQQSPTQQQQPQQQPPPPPRAVSLQPPTSGTRVVPHHSGSAPAPSSKDLKFGIDRILSAEF 183

  Fly   146 -------------------GYPVGV--------VPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQ 183
                               |.|.||        ..|....:|.:.|    .....|..|||..|.
Mouse   184 DPKVKEGNTLRDLTSLLTGGRPAGVHLAGLQPSAGQFFASLDPISE----ASAILSPLSSNPRNS 244

  Fly   184 GDNSITEFVP-------ENGLPRRL-------RTAYTNTQLLELEKEFHFNKYLCRPRRIEIAAS 234
            ..:...:..|       ::.:|:..       |..::|.|...|||.|...||:.:|.|.::||.
Mouse   245 VQHQFQDTFPGPYAVLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAM 309

  Fly   235 LDLTERQVKVWFQNRRMK--HKRQTLSKTDDEDNKDSLKGD------------DDQSDSNSNSKK 285
            |.||:.||||||||||||  |.::..::.|    ||...|:            :::|.|.|..:.
Mouse   310 LGLTDAQVKVWFQNRRMKWRHSKEAQAQKD----KDKEAGEKPSGGVPAEGEREERSPSRSEGEA 370

  Fly   286 SCQGCELPSDDI-PDSTSNSRGHNNNTPSATNNNPSAGNLTPNSSLETGISSNLMGSTTVSASNV 349
            ..:..:..|.|: |..|..:.|...:....|....||......:|..|..||....||    |::
Mouse   371 ESESSDSESLDMAPSDTERTEGTERSLHQTTVIKASAAGALITASSSTSGSSFSFSST----SSL 431

  Fly   350 ISADSSVASSVSLDEDIEE----------SSP 371
            .|.::.|.|:.||..:..|          |||
Mouse   432 GSGNTHVGSASSLGGNCSELPSAHQPSVTSSP 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	29/64 (45%)
Hlx	NP_032276.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..169		8/48 (17%)
		Homeodomain	270..330	CDD:459649	28/59 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	328..401		13/76 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	413..476		16/55 (29%)