Protein Alignment pb and Dlx5

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_034186.2
• Gene: Dlx5 / 13395
• MGIID: 101926
• Length: 289
• Species: Mus musculus
• Alignment Length: 308
• Identity: 78/308 - (25%)
• Similarity: 129/308 - (41%)
• Gaps: 68/308 - (22%)

  Fly    60 GIGQQGVP---------PVPSVLMV---NKMTPNCDKRSA-DTAYWMTASEGGFINSQPSMAEFL 111
            |:..:.||         |.|:...:   ::.:|...:.|| |:.|:           .|:.|...
Mouse     3 GVFDRRVPSIRSGDFQAPFPTSAAMHHPSQESPTLPESSATDSDYY-----------SPAGAAPH 56

  Fly   112 NHLSPESPKIGTPVGSGAIGGVGVNVNVNVGVGVGYPVGVVPQTPDGMDSVPEY----PWMKEKK 172
            .:.||.|...|..:........|||     |...|||.          .:..:|    |:.:...
Mouse    57 GYCSPTSASYGKALNPYQYQYHGVN-----GSAAGYPA----------KAYADYGYASPYHQYGG 106

  Fly   173 TSRKSSNNNNQGDNSITEFVPE----NGLPRRL---RTAYTNTQLLELEKEFHFNKYLCRPRRIE 230
            ...:..:..:|.:..:.|  ||    ||.|:::   ||.|::.||..|::.|...:||..|.|.|
Mouse   107 AYNRVPSATSQPEKEVAE--PEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAE 169

  Fly   231 IAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSDSNSNSKKSCQGCELPSD 295
            :||||.||:.|||:||||:|.|.|:  :.|..:...:.|         .:|:...:|...:.|:.
Mouse   170 LAASLGLTQTQVKIWFQNKRSKIKK--IMKNGEMPPEHS---------PSSSDPMACNSPQSPAV 223

  Fly   296 DIPDSTSNSRGHNNNTPSATNNNPSAGNLTPNS-----SLETGISSNL 338
            ..|..:|.|..|:.:....|:|...|.:...||     |..:.|:|:|
Mouse   224 WEPQGSSRSLSHHPHAHPPTSNQSPASSYLENSASWYPSAASSINSHL 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	27/58 (47%)
Dlx5	NP_034186.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..49		10/56 (18%)
		DLL_N	32..118	CDD:463567	20/111 (18%)
		Homeodomain	138..194	CDD:459649	27/55 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	198..253		11/63 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	270..289		1/2 (50%)