Protein Alignment Taf1 and BDF1

DIOPT Version :10

• Sequence 1: NP_001246952.1
• Gene: Taf1 / 40813
• FlyBaseID: FBgn0010355
• Length: 2172
• Species: Drosophila melanogaster
• Sequence 2: NP_013503.1
• Gene: BDF1 / 851115
• SGDID: S000004391
• Length: 686
• Species: Saccharomyces cerevisiae
• Alignment Length: 736
• Identity: 147/736 - (19%)
• Similarity: 268/736 - (36%)
• Gaps: 203/736 - (27%)

  Fly  1410 SGMQSSLSQSNPS--LADDFDEQSEKEMTMDDDDLVNVDGTKVTLSSKILKRHG---------GD 1463
            |.::..:.|.:||  ||:: :..:..::.:..   ..:||..:|.|...|..:|         |:
Yeast    24 SNLKRPIDQGDPSNGLAEE-ENPANNQLHLKK---ARLDGDALTSSPAGLAENGIEGATLAANGE 84

  Fly  1464 DGKRRSGSSSGFTLKVPRDAMGKKKRRVGGDLHCDYLQRHNK-------------------TANR 1509
            :|...:||.:      ..:..|.||...|.....:.|..::|                   ..|.
Yeast    85 NGYNATGSGA------EDEQQGLKKEEGGQGTKQEDLDENSKQELPMEVPKEPAPAPPPEPDMNN 143

  Fly  1510 RRTDPV---VVLSSILEIIHNELRSMPDVSPFLFPVSAKK--VPDYYRVVTKPMDLQTMREYIRQ 1569
            ...:|:   ....::|.|  ..::.:.|..|||.||...|  :|.|:..:.:||||.|:...:..
Yeast   144 LPQNPIPKHQQKHALLAI--KAVKRLKDARPFLQPVDPVKLDIPFYFNYIKRPMDLSTIERKLNV 206

  Fly  1570 RRYTSREMFLEDLKQIVDNSLIYNGPQSAYTLAAQRMFSSCFE-------------LLAE----- 1616
            ..|...|...||...:|:||:.:|||.:..:..|:.:.:| ||             ::|:
Yeast   207 GAYEVPEQITEDFNLMVNNSIKFNGPNAGISQMARNIQAS-FEKHMLNMPAKDAPPVIAKGRRSS 270

  Fly  1617 -REDKLM----------RLEKAINPLLDDDD-------------QVALSF---IFDKLHSQIKQL 1654
             :||..:          |.::.|:|....|.             |.|:.|   :..:|.:: |..
Yeast   271 AQEDAPIVIRRAQTHNGRPKRTIHPPKSKDIYPYESKKPKSKRLQQAMKFCQSVLKELMAK-KHA 334

  Fly  1655 PESWPFLKPVN--KKQVKDYYTVIKRPMDLETIGKNIEAHRYHSRAEYLADIELIATNCEQYNGS 1717
            ..::|||:||:  ...:..|:..:|.||||.||.|.:...:|.:..::..|:.|:..||..:|..
Yeast   335 SYNYPFLEPVDPVSMNLPTYFDYVKEPMDLGTIAKKLNDWQYQTMEDFERDVRLVFKNCYTFNPD 399

  Fly  1718 DTRYTKFSKKILEYAQTQLIEFSEHCGQLENNIAKTQERARENAPEFDEAWGN----DDYNFDRG 1778
            .|                ::....|  :||.              .|:..|.:    |||:.|..
Yeast   400 GT----------------IVNMMGH--RLEE--------------VFNSKWADRPNLDDYDSDED 432

  Fly  1779 SRASSPGDDYIDVEGHGGHASSSNSIHRSMGAEAGSSHTA--------------PAVRKPAPPGP 1829
            ||...   ||.|.|.....:....:|..:...:......|              ..:||......
Yeast   433 SRTQG---DYDDYESEYSESDIDETIITNPAIQYLEEQLARMKVELQQLKKQELEKIRKERRLAR 494

  Fly  1830 GEVKRG-RGRPRKQRDPVEEVKSQNPVKRGRGRPRKDSLASNMSHTQAYFLDE---DLQCS---- 1886
            |..||| |.:.|.        .|:|...:|| |.:|:.|.:.:::.....:.|   ||..|
Yeast   495 GSKKRGKRSKGRS--------GSKNASSKGR-RDKKNKLKTVVTYDMKRIITERINDLPTSKLER 550

  Fly  1887 ----------TDDEDDDEEEDFQEVSEDENNAASILD----QGERINAPADAMDGMFDPKNIKTE 1937
                      ...|||:.|.|...:  |.:...::.:    |.|..:..::.:||       .:.
Yeast   551 AIDIIKKSMPNISEDDEVELDLDTL--DNHTILTLYNTFFRQYESSSGASNGLDG-------TSG 606

  Fly  1938 IDLEAHQMAEEPIGEDDSQQVAEAMVQLSGVGGYYAQQQQDESMDVDPNYDPSDFLAMHKQRQSL 2002
            :..:|..::  |......::.::|:            .|:::|..::...:....|.........
Yeast   607 VTRDASSLS--PTSAGSRKRRSKAL------------SQEEQSRQIEKIKNKLAILDSASPLSQN 657

  Fly  2003 GEPSSLQGAFTNFLSHEQDDN 2023
            |.|..:|.|..|..|...||:
Yeast   658 GSPGQIQSAAHNGFSSSSDDD 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Taf1	NP_001246952.1	TBP-binding	8..76	CDD:462723
		DUF3591	652..1115	CDD:463476
		zf-CCHC_6	1388..>1418	CDD:464616	1/7 (14%)
		Bromo_TFIID	1518..1629	CDD:99943	34/141 (24%)
		Bromo_TFIID	1640..1751	CDD:99943	27/115 (23%)
BDF1	NP_013503.1	COG5076	1..373	CDD:227408	80/362 (22%)
		Bromodomain	<339..417	CDD:445827	25/109 (23%)
		PTZ00108	<386..647	CDD:240271	56/327 (17%)
		BET	527..589	CDD:435704	10/63 (16%)