Protein Alignment Taf1 and HAF01

DIOPT Version :10

• Sequence 1: NP_001246952.1
• Gene: Taf1 / 40813
• FlyBaseID: FBgn0010355
• Length: 2172
• Species: Drosophila melanogaster
• Sequence 2: NP_174552.1
• Gene: HAF01 / 840169
• AraportID: AT1G32750
• Length: 1919
• Species: Arabidopsis thaliana
• Alignment Length: 2180
• Identity: 470/2180 - (21%)
• Similarity: 741/2180 - (33%)
• Gaps: 825/2180 - (37%)

  Fly     2 EMESDNSDDEGSIGNGLDLTGILFGNIDSEGRLLQDDDGEGRGGTGFDAELRENIGSLS-KLGLD 65
            |..||:.|:......|.:| |.:|||:|:.|.|..|         ..|.:.:|::.:|: |||
plant    12 ETSSDDDDEYEDNSRGFNL-GFIFGNVDNSGDLDAD---------YLDEDAKEHLSALADKLG-- 64

  Fly    66 SMLLEVIDLKEAEPPSDDEEEEDARPSAVSASEGMSAFDALKAGVKREDGAVKAQDDAIDYSDIT 130
            |.|.::..|.::|..:.|..|:|              :|             :..:||:||.||.
plant    65 SSLPDINLLAKSERTASDPAEQD--------------YD-------------RKAEDAVDYEDID 102

  Fly   131 E---------LSEDCPRTPPEE--------------TSTYDDLEDAIPASKVEAKLREDIAQIFK 172
            |         :||:....|.:|              .|.:|| ||    ...|.:..|:.|.:.|
plant   103 EEYDGPEVQVVSEEDHLLPKKEYFSTAVALGSLKSRASVFDD-ED----YDEEEEQEEEQAPVEK 162

  Fly   173 GLCNSCQSDTITFAPLRLGSDLLLYRENNSHFVAAKDDKELMPPPSAPMRSGSGGGIEEPAKSND 237
            .|      :|....|                 |..|:||.|              ..||.|...|
plant   163 SL------ETEKREP-----------------VVLKEDKAL--------------EYEEEASILD 190

  Fly   238 ASSPSDDSKSTDSKDADRKLDTPLAD----ILPSKYQNVDVRELFPDFRPQKVLRFSRLFGPGKP 298
            ..... |::....::.|..|:..|.|    .||:.|....:          .:|:||.:|...:|
plant   191 KEDHM-DTEDVQEEEVDELLEGTLDDKGATPLPTLYVEDGM----------VILQFSEIFAIHEP 244

  Fly   299 TSLPQIWRHVRKRRRKRNQ---SRDQ-KTTNTGGSDSPSDTEEPRKRGFSLHYAAEPTPAECMSD 359
               ||      ||.|:.|:   .||: |:.:.                           :|.:.|
plant   245 ---PQ------KRDRRENRYVTCRDKYKSMDI---------------------------SELVED 273

  Fly   360 DEDKLLGDFNSEDVRPEGPDNGENSDQKPKVADWRFGPAQIWYDMLEVPDSGEGFNYGFKTKAAS 424
            ||:.||......|...|..|                      ...|:||..   ...|.:...||
plant   274 DEEVLLKSHGRIDTHVEQAD----------------------LIQLDVPFP---IREGLQLVKAS 313

  Fly   425 TSSQPQLKDERRVKSPEDD------VEDPSIADDAFLMVSQL----------HWEDDVVWD---- 469
            |......:.....|...|.      ::...|.|::.|..|||          .||..::|:
plant   314 TIGGITPESREFTKLGRDSCIMGELLKQDFIDDNSSLCQSQLSMQVFPLDQHEWERRIIWEHSPE 378

  Fly   470 -----------GNDIKAKVLQKLNSKTN-----------------------AAGWLPSSGSRTAG 500
                       |.:.:..:::..||:|.                       :|..|.|.|||
plant   379 ISGNSGEIFEPGLEPEGMLVKGTNSETEQESLNVVNSRVQVQADNNMFVPFSANLLESFGSR--- 440

  Fly   501 AFSQPGKPSMPVGSGSSKQGSGASSKKAQQNAQAKPAEAPDDTW--------------------- 544
                          ||  |.:..|:.|::.:.|....|:   .|
plant   441 --------------GS--QSTNESTNKSRHHPQLLRLES---QWDENHLSGNDEAGVKKIKRLEK 486

  Fly   545 -----YSLFPVENEELIYYKWEDEVIWDAQQVSKVPKPKVLTLDPNDENIILGIPDDIDPSKINK 604
                 :|...:...:|....|.|.:|||:::  ::.:.| |..|..||.::..|.|:
plant   487 DALGRFSRLVLRERDLGDEAWLDSIIWDSEK--ELSRSK-LIFDLQDEQMVFEIFDN-------- 540

  Fly   605 STGPPPKIKIPHPHVKKSKILLGKAGVINVLAEDTPPPPPKSPDRD-----------PFNISNDT 658
                           ::||.|...||.:.|....      ||.|..           .||:|||.
plant   541 ---------------EESKNLQLHAGAMIVSRSS------KSKDETFQEGCESNSGWQFNLSNDK 584

  Fly   659 YY-TPKTEPTLRLKVGGNLIQ-----HSTPVVELRAPFVPTHMGPMKLRAFHRPPLKKYSHG--- 714
            :| ..|:...|:.....:.:.     ||.|.::|:.  :.:.:....:..||||....|.|.
plant   585 FYMNGKSSQQLQANTNKSSVHSLRVFHSVPAIKLQT--MKSKLSNKDIANFHRPKALWYPHDNEL 647

  Fly   715 PMAQSIPHPVFPLLKTIAK----------------------------------------KAKQRE 739
            .:.|....|....:|.|.|                                        |.|:.:
plant   648 AIKQQGKLPTRGSMKIIVKSLGGKGSKLHVGIEESVSSLRAKASRKLDFKETEAVKMFYKGKELD 712

  Fly   740 VERIASG-------------------------GGDVFFMRNP------EDLSGRDGDIVLAEFCE 773
            .|:..:.                         .|:...:|.|      .|||.:||.:.|.|:||
plant   713 DEKSLAAQNVQPNSLVHLIRTKVHLWPWAQKLPGENKSLRPPGAFKKKSDLSTKDGHVFLMEYCE 777

  Fly   774 EHPPLINQVGMCSKIKNYYKRKAEKDS-----GPQDFVYGEVAF---AHTSPFLGILHPGQCIQA 830
            |.|.:::..||.:.:..||::.:.:|.     ..|....|.|..   ...|||||.:|.|....:
plant   778 ERPLMLSNAGMGANLCTYYQKSSPEDQRGNLLRNQSDTLGNVMILEPGDKSPFLGEIHAGCSQSS 842

  Fly   831 IENNMYRAPIYPHKMAHNDFLVIRT-RNNYWIRSVNSIYTVGQECPLYEVPGPNSKRANNFTRDF 894
            :|.|||:|||:|.::...|:|::|: :....:|.::.|..|||:.|..||..|.||....:..:.
plant   843 VETNMYKAPIFPQRLQSTDYLLVRSPKGKLSLRRIDKIVVVGQQEPRMEVMSPGSKNLQTYLVNR 907

  Fly   895 LQVFIYRLFWKSRDNPRRIRMDDIKQAFPAHSESSIRKRLKQCADFKRTGMDSNWWVIKPEFRLP 959
            :.|::||.|:|.......|..|::...|...:::.|:|.:|..|.:||.....::|..|.....|
plant   908 MLVYVYREFFKRGGGEHPIAADELSFLFSNLTDAIIKKNMKIIACWKRDKNGQSYWTKKDSLLEP 972

  Fly   960 SEEEIRAMVSPEQCCAYFSMIAAEQRLKDAGYGEKFLFA---------PQEDDDEEAQLKLDDEV 1015
            .|.|::.:|:||..|:|.||:|...|||..|.....|.|         |.|.....|...::.|:
plant   973 PESELKKLVAPEHVCSYESMLAGLYRLKHLGITRFTLPASISNALAQLPDEAIALAAASHIEREL 1037

  Fly  1016 KVAPWNTT----------RAYIQAMRGKCLLQLSGPADPTGCGEGFSYVR-VPNKPT----QTKE 1065
            ::.|||.:          ||.|:.      |:::|..||:|.|.|||||| .|..|.    ..|:
plant  1038 QITPWNLSSNFVACTNQDRANIER------LEITGVGDPSGRGLGFSYVRAAPKAPAAAGHMKKK 1096

  Fly  1066 EQESQPKRSVTGTDADLRRLPLQRAKELLRQFKVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEE- 1129
            ....:...:|||||||||||.::.|:|:|.:|.||:|.|.|.:||..|.::|.||:|:|.:|.:
plant  1097 AAAGRGAPTVTGTDADLRRLSMEAAREVLIKFNVPDEIIAKQTRWHRIAMIRKLSSEQAASGVKV 1161

  Fly  1130 ---GMDKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLASSEVLSTDEAESSASEESDLEELGKN 1191
               .:.|::||.|.|..:.|::.:|:||.|:|   |.|.|......||.||.....|||:....:
plant  1162 DPTTIGKYARGQRMSFLQMQQQAREKCQEIWD---RQLLSLSAFDGDENESENEANSDLDSFAGD 1223

  Fly  1192 LENML----------SNKKTSTQLS-------RER-------EELERQ-----ELLRQLDEEHGG 1227
            |||:|          ||...:.:|.       |.|       ||:|.:     ||.|.|.::...
plant  1224 LENLLDAEEGGEGEESNISKNDKLDGVKGLKMRRRPSQVETDEEIEDEATEYAELCRLLMQDEDQ 1288

  Fly  1228 PSGSGGAKG---AKGKDDPGQQMLATNNQGRILRITRTFRGNDGKEYTRVETVRRQPVIDAYIKI 1289
            .......||   ..|...|.:..:|..:               |:...:...:.::|       |
plant  1289 KKKKKKMKGVGEGMGSYPPPRPNIALQS---------------GEPVRKANAMDKKP-------I 1331

  Fly  1290 RTTKDEQFIKQFATLDEQQKEEMKREKRRIQEQLRRIKRNQERERLAQLAQNQKLQPGGMPTSLG 1354
            ....|..|:...:|:         ::.|.:...::..|..|.:|....|.|.:|::
plant  1332 AIQPDASFLVNESTI---------KDNRNVDSIIKTPKGKQVKENSNSLGQLKKVK--------- 1378

  Fly  1355 DPKSSGGHSHKERDSGYKEVSPSRKKFKLKPDLKLKCGACGQVGHMRTNKACPLY--------SG 1411
                    ...|....:||...:|:.|        .||||||.|||||||.||.|        .|
plant  1379 --------ILNENLKVFKEKKSARENF--------VCGACGQHGHMRTNKHCPRYRENTESQPEG 1427

  Fly  1412 MQSSLSQSNPSLAD-----------------------DFDE------------------------ 1429
            :....|...||.::                       ..||
plant  1428 IDMDKSAGKPSSSEPSGLPKLKPIKNSKAAPKSAMKTSVDEALKGDKLSSKTGGLPLKFRYGIPA 1492

  Fly  1430 -------------QSEKEMTMDDDDLVNVDG--TKVTLSSKILKRHGGDDGKRRSGS-------- 1471
                         .||:.:..|.|..:....  :|:.:|||...:....:.:|||.|
plant  1493 GDLSDKPVSEAPGSSEQAVVSDIDTGIKSTSKISKLKISSKAKPKESKGESERRSHSLMPTFSRE 1557

  Fly  1472 -------------------------SSGFTLKVPRDAMG-------------------------- 1485
                                     ||..|:.:||.::.
plant  1558 RGESESHKPSVSGQPLSSTERNQAASSRHTISIPRPSLSMDTDQAESRRPHLVIRPPTEREQPQK 1622

  Fly  1486 ----------------------------------------------------------------- 1485
                                                                             
plant  1623 KLVIKRSKEMNDHDMSSLEESPRFESRKTKRMAELAGFQRQQSFRLSENSLERRPKEDRVWWEEE 1687

  Fly  1486 -----------------------------------------------------KKKRRVGGDLHC 1497
                                                                 |||:::..::..
plant  1688 EISTGRHREVRARRDYDDMSVSEEPNEIAEIRRYEEVIRSEREEEERQKAKKKKKKKKLQPEIVE 1752

  Fly  1498 DYLQRHNKTAN------------------------------RRRTDPVVVLSSILEIIHNELRSM 1532
            .||:.:....|                              :||....|.|::|||.|.:.||..
plant  1753 GYLEDYPPRKNDRRLSERGRNVRSRYVSDFERDGAEYAPQPKRRKKGEVGLANILERIVDTLRLK 1817

  Fly  1533 PDVSP-FLFPVSAKKVPDYYRVVTKPMDLQTMREYIRQRRYTSREMFLEDLKQIVDNSLIYN-GP 1595
            .:||. ||.|||.|:.|||..:|..||||.|:|:.:|:..|.:||.|..|:.||..|:.:|| |.
plant  1818 EEVSRLFLKPVSKKEAPDYLDIVENPMDLSTIRDKVRKIEYRNREQFRHDVWQIKYNAHLYNDGR 1882

  Fly  1596 QSAYTLAAQRMFSSCFELLAEREDKLMRLEKAINP 1630
            .......|.::...|..||.:.||:|...||.|:|
plant  1883 NPGIPPLADQLLEICDYLLDDYEDQLKEAEKGIDP 1917

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Taf1	NP_001246952.1	TBP-binding	8..76	CDD:462723	20/68 (29%)
		DUF3591	652..1115	CDD:463476	158/575 (27%)
		zf-CCHC_6	1388..>1418	CDD:464616	17/37 (46%)
		Bromo_TFIID	1518..1629	CDD:99943	46/112 (41%)
		Bromo_TFIID	1640..1751	CDD:99943
HAF01	NP_174552.1	TBP-binding	24..>64	CDD:462723	14/49 (29%)
		DUF3591	578..1146	CDD:463476	158/575 (27%)
		zf-CCHC_6	1399..1432	CDD:464616	17/32 (53%)
		Bromodomain	1806..1901	CDD:99922	38/94 (40%)