Protein Alignment Taf1 and taf1

DIOPT Version :10

• Sequence 1: NP_001246952.1
• Gene: Taf1 / 40813
• FlyBaseID: FBgn0010355
• Length: 2172
• Species: Drosophila melanogaster
• Sequence 2: XP_012824624.1
• Gene: taf1 / 100496377
• XenbaseID: XB-GENE-952372
• Length: 1949
• Species: Xenopus tropicalis
• Alignment Length: 2224
• Identity: 993/2224 - (44%)
• Similarity: 1324/2224 - (59%)
• Gaps: 381/2224 - (17%)

  Fly     3 MESDNSDDEGSIGNGLDLTGILFGNIDSEGRLLQDDDGEGRGGTGFDAELRENIGSLSKLGLDSM 67
            |....||:|    ....|||.|||||:.:|:|  :||      :..|.|.::::..|..|||.::
 Frog     1 MSDSESDEE----RPFSLTGFLFGNINEDGQL--EDD------SVLDKESKKHLAGLGALGLGNL 53

  Fly    68 LLEVIDLKEAEPPSDDEEEEDARPSAVSASEGMSAFDALKAGVKREDGAVKAQDDAIDYSDITEL 132
            |.|:..       |.||..|         :||::..|         ||.||:.|||||||||.|:
 Frog    54 LTEITS-------SVDEGAE---------TEGVNVDD---------DGWVKSTDDAIDYSDINEV 93

  Fly   133 SED-------------CPRTPPEETSTYD-DLEDAIPASKVEAKLR-----EDIAQIFKGLCNSC 178
            :||             ..|...::...|| |.||      :::||.     ..:         :|
 Frog    94 AEDESRRYRQAMGNLNLSRRTDDDDDDYDADCED------IDSKLMPPPPPPPV---------TC 143

  Fly   179 QSDTITFAPLRLGSDLLLYRENNSHFVAAKDDKELMPPPSAPMRSGSGGGIEEPAKSNDASS--- 240
            :.|                 |:.....||::|.:.:..||....|.|.....:.:.|:|:.|
 Frog   144 KKD-----------------EDRPAVSAAQEDNDGIILPSIIASSSSSLERVDFSSSSDSESEIG 191

  Fly   241 PSDDSKSTDSKDADRKLDTPLADI--------LPSKYQNVDVRELFPDFRPQKVLRFSRLFGPGK 297
            |.|  ||.:.|...::|..|||.|        |||      |..|||:|||.|||||.|||||||
 Frog   192 PQD--KSKEEKRERKQLTLPLAGIMQRDATKQLPS------VTALFPEFRPGKVLRFLRLFGPGK 248

  Fly   298 PTSLPQIWRHVRKRRRKRNQSRDQKTTNTGGSDSPSDTEEPRKRGFSLHYAAEPTPAECMSDDED 362
              |:..:||..|::|||:::...|:|....|.::.:..|  :|..:...||..|.|.:|:||||.
 Frog   249 --SVLSVWRSARRKRRKKHREMVQETPAKEGEETEAPVE--KKSCWEYEYAPPPPPEQCLSDDEI 309

  Fly   363 KLLGDFNSEDVRPEGPDNGENSDQKPKVADWRFGPAQIWYDMLEVPDSGEGFNYGFKTKAASTSS 427
            .::.....:..:..| |..:.:|.||:||:||:||||:|||||.||:.|..|:||||.|..:.:.
 Frog   310 TMMAPVEPKFSQSTG-DIDKVADTKPRVAEWRYGPAQLWYDMLGVPEDGSSFDYGFKLKENNDTE 373

  Fly   428 QPQLKDERRVKSPEDDVEDPSIADDAFLMVSQLHWEDDVVWDGNDIKAKVLQKLNSKTNAAGWLP 492
            :.:::.|..|::|:...:   ..|:.||||:||.|||||:|:|.|:|.|..:  ..|.:.|||||
 Frog   374 ENEMQTEEPVEAPDSPTQ---FLDEHFLMVTQLQWEDDVIWNGEDVKHKATK--TQKASLAGWLP 433

  Fly   493 SSGSRTAGAF-SQPG----------------KPSMPVGSGSSKQGSGASSKKAQQNAQAKPAEAP 540
            ||.:|.|.|: :|.|                ||:||   |:.....|......:|.|..:    .
 Frog   434 SSMTRNATAYNAQQGLNRTGSLLNLPTPLVQKPAMP---GALISVKGKEKHPTEQQASIE----E 491

  Fly   541 DDTWYSLFPVENEELIYYKWEDEVIWDAQQVSKVPKPKVLTLDPNDENIILGIPDDIDPSKINKS 605
            |..|:|:||::||||:|.:|||.:|||.|.:.::..|.||.||||||||||.|||:    |...:
 Frog   492 DRPWFSIFPIDNEELVYGRWEDNIIWDDQAMDRILDPPVLNLDPNDENIILEIPDE----KEETT 552

  Fly   606 TGPPPKIKIPHPHVKKSKILLGKAGVINVLAEDTPPPPPKSPD-RDPFNISNDTYYTPKTEPTLR 669
            :..|.|.......:|||:|||||.|||    ::.|......|: :||:|:|||.:|.|| :..||
 Frog   553 SNSPSKESKKESSLKKSRILLGKTGVI----KEEPQQNMSQPEVKDPWNLSNDEFYYPK-QQGLR 612

  Fly   670 LKVGGNLIQHSTPVVELRAPFVPTHMGPMKLRAFHRPPLKKYSHGPMAQSIPHPVFPLLKTIAKK 734
            ...|||:||||.|.||||.||.||||||||||.||||||||||.|.::|..|||...|||.|.||
 Frog   613 GTFGGNIIQHSIPAVELRQPFFPTHMGPMKLRLFHRPPLKKYSFGALSQPGPHPSQSLLKHIKKK 677

  Fly   735 AKQREVERIASGGGDVFFMRNPEDLSGRDGDIVLAEFCEEHPPLINQVGMCSKIKNYYKRKAEKD 799
            ||.||.||.|||||::||||..:||:|:|||::|||:.||:|||:.||||.||||||||||..||
 Frog   678 AKMREQERQASGGGEMFFMRTSQDLTGKDGDLILAEYSEENPPLMMQVGMASKIKNYYKRKPGKD 742

  Fly   800 SGPQDFVYGEVAFAHTSPFLGILHPGQCIQAIENNMYRAPIYPHKMAHNDFLVIRTRNNYWIRSV 864
            .|..|..:||..:.|||||||.|||||.:||.|||::|||||.|||...|||:||||..|:||.:
 Frog   743 PGAPDCKFGETVYCHTSPFLGSLHPGQLLQAFENNLFRAPIYLHKMTETDFLIIRTRQGYYIRDI 807

  Fly   865 NSIYTVGQECPLYEVPGPNSKRANNFTRDFLQVFIYRLFWKSRDNPRRIRMDDIKQAFPAHSESS 929
            ..|:.|||:|||:|||||||||||...|||||||||||||||:|.||||||:|||:|||:|||||
 Frog   808 VDIFVVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSKDRPRRIRMEDIKKAFPSHSESS 872

  Fly   930 IRKRLKQCADFKRTGMDSNWWVIKPEFRLPSEEEIRAMVSPEQCCAYFSMIAAEQRLKDAGYGEK 994
            ||||||.|||||||||||||||:||:||||:||||||||||||||||:|||||||||||||||||
 Frog   873 IRKRLKLCADFKRTGMDSNWWVLKPDFRLPTEEEIRAMVSPEQCCAYYSMIAAEQRLKDAGYGEK 937

  Fly   995 FLFAPQEDDDEEAQLKLDDEVKVAPWNTTRAYIQAMRGKCLLQLSGPADPTGCGEGFSYVRVPNK 1059
            ..|||:|:::|:.|:|:||||:.||||||||:|.||:|||||:::|.|||||||||||||::|||
 Frog   938 SFFAPEEENEEDFQMKIDDEVRTAPWNTTRAFIAAMKGKCLLEVTGVADPTGCGEGFSYVKIPNK 1002

  Fly  1060 PTQTK-EEQESQP-KRSVTGTDADLRRLPLQRAKELLRQFKVPEEEIKKLSRWEVIDVVRTLSTE 1122
            |||.| :::|.|| |::|||||||||||.|:.||:|||:|.||||||||||||||||||||:|||
 Frog  1003 PTQQKQDDKEPQPVKKTVTGTDADLRRLSLKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTE 1067

  Fly  1123 KAKAGEEGMDKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLASSEVLSTDEAESSASEESDLEE 1187
            :|::||..|.||:||:|||:|||||||||||||||||||:||.|:|||||| .:||::|:||.||
 Frog  1068 QARSGEGPMSKFARGSRFSVAEHQERYKEECQRIFDLQNKVLESAEVLSTD-TDSSSAEDSDFEE 1131

  Fly  1188 LGKNLENMLSNKKTSTQLSREREELERQELLRQL---------------DEEHGGPSGSGGAKGA 1237
            :|||:||||.|||||:||||||||.||:||.|.|               .:|..|...|..|.|.
 Frog  1132 MGKNIENMLQNKKTSSQLSREREEQERKELQRMLMGEDSGNDKERSRKDKKERKGLGASSAASGG 1196

  Fly  1238 KGKDDPGQQMLATNN--QGRILRITRTFRGNDGKEYTRVETVRRQPVIDAYIKIRTTKDEQFIKQ 1300
            ..|||....:.:.|:  .||.|:|.||||..|||||.|.||||:..|||||.:||||||::||::
 Frog  1197 SHKDDDTASVTSLNSAASGRRLKIYRTFRDEDGKEYVRCETVRKPSVIDAYSRIRTTKDDEFIRK 1261

  Fly  1301 FATLDEQQKEEMKREKRRIQEQLRRIKRNQERERLAQLAQNQKLQPGGMPTSLGDPKSSGGHSHK 1365
            ||..|||.:|||::|:|||||||||:|||||:|:|.                 |.|
 Frog  1262 FALFDEQHREEMRKERRRIQEQLRRLKRNQEKEKLR-----------------GPP--------- 1300

  Fly  1366 ERDSGYKEVSPSRKKFKLKPDLKLKCGACGQVGHMRTNKACPLYSGMQSSLSQSNP-SLADDFDE 1429
                   |..|  ||.|.:|||||||||||.:|||||||.||||  .|::...||| ::.::.:|
 Frog  1301 -------EKKP--KKMKERPDLKLKCGACGAIGHMRTNKFCPLY--YQTNAPPSNPVAMTEEQEE 1354

  Fly  1430 QSEKEMT-MDDDDLVNVDGTKVTLSSKILKRHGGDDGKRRSGSSSGFTLKVPRDAM-GKKKRRVG 1492
            :.||.:. .|:::|:.|:|||:.|..::::  ..|:.:|:|     ..||.|:..: .|||||||
 Frog  1355 ELEKTVIHNDNEELIKVEGTKIVLGKQLIE--SADEVRRKS-----LVLKFPKQQLPQKKKRRVG 1412

  Fly  1493 GDLHCDYLQRHNKTANRRRTDPVVVLSSILEIIHNELRSMPDVSPFLFPVSAKKVPDYYRVVTKP 1557
            ..:|||||.|.:|:.:||||||:|.|||:||.|.|::|.||:..||..||:||.|.|||::|..|
 Frog  1413 STVHCDYLNRPHKSIHRRRTDPMVTLSSVLESIINDMRDMPNTYPFHSPVNAKVVKDYYKIVINP 1477

  Fly  1558 MDLQTMREYIRQRRYTSREMFLEDLKQIVDNSLIYNGPQSAYTLAAQRMFSSCFELLAEREDKLM 1622
            |||||:||.:|:|.|.|||.|.|.::.||.||::||||:.:.|...|.|...|.|.|.|:||||.
 Frog  1478 MDLQTLRENVRKRMYPSREEFREAVELIVKNSILYNGPKHSLTQICQAMLELCEEKLREKEDKLA 1542

  Fly  1623 RLEKAINPLLDDDDQVALSFIFDKLHSQ-IKQLPESWPFLKPVNKKQVKDYYTVIKRPMDLETIG 1686
            |||||||||||||||||.|||.|.:.:| :..:|:||||..|||||.|.|||.||..|||||||.
 Frog  1543 RLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIR 1607

  Fly  1687 KNIEAHRYHSRAEYLADIELIATNCEQYNGSDTRYTKFSKKILEYAQTQLIEFSEHCGQLENNIA 1751
            :||..|:|.:|..:.||:.||..|..:|||.|::|:|.:::|:......|:|:.||..|||.:|:
 Frog  1608 QNISKHKYQNREFFQADVNLIYANSIKYNGQDSQYSKTAQEIVNICIQTLLEYDEHLTQLEKDIS 1672

  Fly  1752 KTQERARENAPEFDEAWGNDDYNFDRGSRASSPG------DDYIDVEGHGGHASSSNSIHRSMGA 1810
            ..:|.|.|.|         |..:.|    ..:||      .||.|          :|:.| ||..
 Frog  1673 TAKEAALEEA---------DLESLD----PMTPGPYTPQPPDYYD----------TNTSH-SMSR 1713

  Fly  1811 EAG-----SSHTAPAVRKPAPPGPGEVKRGRGRPRKQRDPVEEVKSQNPVKRGRGRPRKDSLASN 1870
            ||.     |:.:|..:                       ....::.::.::.||.|..:|.
 Frog  1714 EASFYQDESNLSATEI-----------------------ATASLEKRSLMRLGRSRMGEDD---- 1751

  Fly  1871 MSHTQAYFLDEDLQCSTDDEDDDEEE----DFQEVSEDENNA----ASILDQGERINAPADAMDG 1927
                    .|.|:: ..:||||.:.:    :.::..||||:.    ||:|.|
 Frog  1752 --------SDVDIE-GYEDEDDGKPKTPAPEVEDAEEDENSVQQPQASVLYQ------------- 1794

  Fly  1928 MFDPKNIKTEIDLEAHQMAEEPIGEDDSQQVAE-------AMVQLSGVGGYYAQQQQDESMDVDP 1985
                       ||   .|:|   ||||....::       :.:|||..|    .....||..:.|
 Frog  1795 -----------DL---LMSE---GEDDEDDGSDEEGDNPFSSIQLSESG----SDSDIESAGIRP 1838

  Fly  1986 NYDPSDFLAMHKQRQSLGEPSSLQGAFTNFLSHEQDDNGPYNPAEASTSAASGADLG---MDASM 2047
            .                 :|..:|         |....|..| .|:..|...|||..   .|:::
 Frog  1839 K-----------------QPHMMQ---------ENTRMGMEN-EESMMSYGEGADASHVLEDSNI 1876

  Fly  2048 AMQM--APEMPVNTMNNGMGIDDDLDISESDEEDD----GSRVRIKKEVFDDGDYALQHQQMGQA 2106
            :.:.  .|:...||.:.........::||.:|::|    |..|..:.::.:|.:.:.:.:.:|..
 Frog  1877 SYESYEEPDPKSNTRDTSFSSMGGYELSEEEEDEDEEHHGPSVLSQVQLSEDEEDSEEFRSIGGD 1941

  Fly  2107 ASQSQIYMVDSSNE 2120
            :.      :||.||
 Frog  1942 SD------IDSDNE 1949

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Taf1	NP_001246952.1	TBP-binding	8..76	CDD:462723	23/67 (34%)
		DUF3591	652..1115	CDD:463476	334/464 (72%)
		zf-CCHC_6	1388..>1418	CDD:464616	20/29 (69%)
		Bromo_TFIID	1518..1629	CDD:99943	61/110 (55%)
		Bromo_TFIID	1640..1751	CDD:99943	52/111 (47%)
taf1	XP_012824624.1	TBP-binding	4..>41	CDD:462723	17/48 (35%)
		DUF3591	596..1060	CDD:463476	334/464 (72%)
		zf-CCHC_6	1314..1349	CDD:464616	23/36 (64%)
		Bromo_TFIID	1438..1549	CDD:99943	61/110 (55%)
		Bromo_TFIID	1560..1671	CDD:99943	52/110 (47%)