DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17917 and PEBP4

DIOPT Version :9

Sequence 1:	NP_649642.1	Gene:	CG17917 / 40778	FlyBaseID:	FBgn0037431	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	NP_001350162.1	Gene:	PEBP4 / 157310	HGNCID:	28319	Length:	227	Species:	Homo sapiens

Alignment Length:	148	Identity:	49/148 - (33%)
Similarity:	71/148 - (47%)	Gaps:	10/148 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 EPSVKWPSAPEN-YYALLMVDPDVPNAITPTHREFLHWMVLNIPGNLLALGDVR----VGYMGAT 127
            ||.||:|.|.:. .|.|:|||||.|:...|..|.:.||:|.:|.|..|..|.::    ..|...:
Human    76 EPIVKFPGAVDGATYILVMVDPDAPSRAEPRQRFWRHWLVTDIKGADLKKGKIQGQELSAYQAPS 140

  Fly   128 PLKGTGTHRFVFLLYKQRDYTKFDFPKLPKHSVKGRSGFETKRFAKKYRFGHPVAGNFFTSQWSP 192
            |...:|.||:.|.:|.|....   ...|||.: |.|..::..||..::..|.|.|...|.:|...
Human   141 PPAHSGFHRYQFFVYLQEGKV---ISLLPKEN-KTRGSWKMDRFLNRFHLGEPEASTQFMTQNYQ 201

  Fly   193 DVPSLIKAISHNARQVAH 210
            |.|:| :|....|.:..|
Human   202 DSPTL-QAPRERASEPKH 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17917	NP_649642.1	PEBP_euk	44..188	CDD:176644	42/124 (34%)
PEBP4	NP_001350162.1	PEBP_euk	46..197	CDD:176644	42/124 (34%)
		Important for secretion. /evidence=ECO:0000269\|PubMed:27033522	188..227		10/32 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	202..227		6/18 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1881
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1557122at2759
OrthoFinder	1	1.000	-	-		FOG0000438
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11362
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X275
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.920