Protein Alignment NPFR and LOC1274295

DIOPT Version :10

• Sequence 1: NP_001246947.1
• Gene: NPFR / 40754
• FlyBaseID: FBgn0037408
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: XP_061501239.1
• Gene: LOC1274295 / 1274295
• VectorBaseID: AGAMI1_004613
• Length: 428
• Species: Anopheles gambiae
• Alignment Length: 439
• Identity: 105/439 - (23%)
• Similarity: 188/439 - (42%)
• Gaps: 65/439 - (14%)

  Fly     4 SMNQT---EPAQLADGEHLSGYASSSNSVRYLDDR---------HPLDYLDLGTVHALNTTAINT 56
            ::|::   |...|.||  |.|......|:|.|...         .|   ...|:.||
Mosquito     9 NLNESFAVEEPSLPDG--LDGVNRIQKSIRLLSGEMIAASAPWTSP---APAGSPHA-------- 60

  Fly    57 SDLNETGSRPLDPVLIDRFLSNRAVDSPWYHMLISMYGVLIVFGALGNTLVVIAVIRKPIMRTAR 121
            .||      .||.|.:|.::...  ..|..:::..::.::.:.|.:||..:|:..:|...||...
Mosquito    61 KDL------LLDEVSVDDYVPYE--QRPETYIVPVVFALIFIVGIVGNGTLVVIFLRHRAMRNIP 117

  Fly   122 NLFILNLAISDLLLCLVTMPLTLMEILSKYWPYGSCSILCKTIAMLQALCIFVSTISITAIAFDR 186
            |.:|.:||::|||:.|:.:||..:....:.||:|..  ||:.....:.:.|.||..::||::.||
Mosquito   118 NTYIFSLALADLLVILICVPLASLIYTLESWPWGDA--LCRVSEFAEEISIGVSVFTLTALSADR 180

  Fly   187 YQVIVYPTRDSLQFVGAVTILAG-IWALALLLASPLFVYKELINTDTPALLQQIGLQDTIPYCIE 250
            |..||.|.| .||......|:|. ||.||::.|.|..|..|::....|        ..||.||..
Mosquito   181 YCAIVNPLR-KLQTRPLTVIVAFLIWVLAIICAIPSAVISEVVVVRLP--------NKTIEYCSP 236

  Fly   251 DWP-SRNGRF--YYSIFSLCVQYLVPILIVSVAYFGIYNKLKSRITVVAVQASSAQRKVERGRRM 312
            ..| :|...:  |.::.:..|.|.:|:.|:.:.|..:.::|.:....:..:.:..|.: .:.|..
Mosquito   237 FGPRTRESSYSKYKTVLNSIVYYFLPLSIIGILYVLMAHRLHTSAREMPGENAGPQSR-SQARAR 300

  Fly   313 KRTNCLLISIAIIFGVSWLPLNFFNLYADMERSPVTQSMLVRY-------AICHMIGMSSACSNP 370
            :....::|:..|:|.|.:||.:...|:..:  :|..:.....:       ..|  :...::|.||
Mosquito   301 RHVARMVITFVIVFIVCFLPHHVVELWFHL--NPHAEDDYDDFWHIFRITGFC--LSFLNSCINP 361

  Fly   371 LLYGWLNDNFRKEFQELLCRCS----DTNVALNGHTTGCNVQAAARRRR 415
            :....::..||:.|...|| |.    ...:.|:.....|.....:..||
Mosquito   362 VALYCVSGVFRQHFHRYLC-CRPMTVQRRIGLSSAGNACETSFVSTIRR 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPFR	NP_001246947.1	7tmA_NPYR-like	88..384	CDD:320331	76/306 (25%)
		TM helix 1	88..114	CDD:320331	4/25 (16%)
		TM helix 2	121..146	CDD:320331	10/24 (42%)
		TM helix 3	161..191	CDD:320331	9/29 (31%)
		TM helix 4	202..223	CDD:320331	8/21 (38%)
		TM helix 5	258..287	CDD:320331	6/30 (20%)
		TM helix 6	310..340	CDD:320331	8/29 (28%)
		TM helix 7	352..377	CDD:320331	4/31 (13%)
LOC1274295	XP_061501239.1	None