DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sec20 and Bnip1

DIOPT Version :9

Sequence 1:	NP_001287187.1	Gene:	Sec20 / 40724	FlyBaseID:	FBgn0037383	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_742161.4	Gene:	Bnip1 / 224630	MGIID:	109328	Length:	228	Species:	Mus musculus

Alignment Length:	219	Identity:	80/219 - (36%)
Similarity:	130/219 - (59%)	Gaps:	11/219 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 QDLIDNNLQAKAIIHDILNSRTSIAELEELNEAGRSKLSAIRKSIERLDDWAR----DTADSALA 73
            |:::..:|:.||:|.||.:....::||.|||...:.|...:::.|:.|:..||    ::....|.
Mouse    14 QEIVKFDLEVKALIQDIRDCSGPLSELTELNTKVKEKFQQLKQRIQELEQSAREQDKESEKQLLL 78

  Fly    74 NEVDDHRDQFSKTLQAFRKANVSTMLEIEKANREELMAITGESELRQRTTTRARHNQGSLVSQEN 138
            .||::|:.|......::||||::..|.|:...:.||  :.|...||||.||:.     ||....:
Mouse    79 QEVENHKKQMLSNQTSWRKANLTCKLAIDNLEKAEL--LQGGDSLRQRKTTKE-----SLAQTSS 136

  Fly   139 DVTEKMLAISRHLSETTQKSAITLETLVASSQNVEATSDELHHTAGSISMSGKLLKKYGRRECTD 203
            .:||.::.|||.:|:..|:|...::|||:||:.:...::|....:|:|.:..||:.||.|||.||
Mouse   137 SITESLMGISRMMSQQVQQSEEAMQTLVSSSRTLLDANEEFKSMSGTIQLGRKLITKYNRRELTD 201

  Fly   204 KMLLFFAFSLFLACVFYIVQKRLF 227
            |:|:|.|.:||||.|.|||:||||
Mouse   202 KLLIFLALALFLATVLYIVKKRLF 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sec20	NP_001287187.1	Sec20	135..226	CDD:112708	38/90 (42%)
Bnip1	NP_742161.4	SNARE_SEC20	132..224	CDD:277218	38/91 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850732
Domainoid	1	1.000	83	1.000	Domainoid score	I8374
eggNOG	1	0.900	-	-		E1_28N8I
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H930
Inparanoid	1	1.050	141	1.000	Inparanoid score	I4477
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55915
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004333
OrthoInspector	1	1.000	-	-		oto95399
orthoMCL	1	0.900	-	-		OOG6_103788
Panther	1	1.100	-	-	LDO	PTHR12825
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3048
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.790