Protein Alignment Rab23 and RAB3B

DIOPT Version :10

• Sequence 1: NP_649574.1
• Gene: Rab23 / 40701
• FlyBaseID: FBgn0037364
• Length: 268
• Species: Drosophila melanogaster
• Sequence 2: NP_002858.2
• Gene: RAB3B / 5865
• HGNCID: 9778
• Length: 219
• Species: Homo sapiens
• Alignment Length: 196
• Identity: 64/196 - (32%)
• Similarity: 107/196 - (54%)
• Gaps: 7/196 - (3%)

  Fly    31 EDDIELAIKVVIVGNGGVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIEIDGEDVRIMLWDTAG 95
            :.:.:...|::|:||..|||:|.:.||....||..:..|:|:||..:.:....:.|::.:|||||
Human    16 DQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAG 80

  Fly    96 QEEFDCITKAYYRGAQASVLVFSTTDRASFDAIKDWKRKVEN-ECNEIPTVIVQNKIDLIEQAVV 159
            ||.:..||.||||||...:|::..|:..||:|::||..:::. ..:....::|.||.|:.|:.||
Human    81 QERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMEEERVV 145

  Fly   160 TADEVETLAKLLNCRLIRTSVKEDINVASVFRYLATKCHQLMTQSYD---QVAGNQQN---SSHP 218
            ..::.:.||:.|.......|.||:|:|...|..|.......|:.|.|   .:.|:.:|   |..|
Human   146 PTEKGQLLAEQLGFDFFEASAKENISVRQAFERLVDAICDKMSDSLDTDPSMLGSSKNTRLSDTP 210

  Fly   219 P 219
            |
Human   211 P 211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab23	NP_649574.1	Rab23_like	50..197	CDD:133306	50/147 (34%)
RAB3B	NP_002858.2	Rab3	22..186	CDD:206657	56/163 (34%)
		Switch 1. /evidence=ECO:0000269|PubMed:35871249, ECO:0007744|PDB:8A4B	45..58		4/12 (33%)
		Switch 2. /evidence=ECO:0000269|PubMed:35871249, ECO:0007744|PDB:8A4B	78..96		12/17 (71%)