Protein Alignment Rab23 and RAB3C

DIOPT Version :10

• Sequence 1: NP_649574.1
• Gene: Rab23 / 40701
• FlyBaseID: FBgn0037364
• Length: 268
• Species: Drosophila melanogaster
• Sequence 2: NP_612462.1
• Gene: RAB3C / 115827
• HGNCID: 30269
• Length: 227
• Species: Homo sapiens
• Alignment Length: 206
• Identity: 61/206 - (29%)
• Similarity: 112/206 - (54%)
• Gaps: 8/206 - (3%)

  Fly    22 AQYNYTSMREDDIELAIKVVIVGNGGVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIEIDGEDV 86
            |:|......:.:.:...|::|:||..|||:|.:.||....||..:..|:|:||..:.:..:.:.:
Human    15 ARYGQKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRI 79

  Fly    87 RIMLWDTAGQEEFDCITKAYYRGAQASVLVFSTTDRASFDAIKDWKRKVEN-ECNEIPTVIVQNK 150
            ::.:|||||||.:..||.||||||...:|::..|:..||:|::||..:::. ..:....::|.||
Human    80 KLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILVGNK 144

  Fly   151 IDLIEQAVVTADEVETLAKLLNCRLIRTSVKEDINVASVFRYLATKCHQLMTQSYD---QVAGNQ 212
            .|:.::.|::.:..:.|.:.|......||.|::|||...|..|.......|::|.:   .:...:
Human   145 CDMEDERVISTERGQHLGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLETDPAITAAK 209

  Fly   213 QNS----SHPP 219
            ||:    :.||
Human   210 QNTRLKETPPP 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab23	NP_649574.1	Rab23_like	50..197	CDD:133306	47/147 (32%)
RAB3C	NP_612462.1	Rab3	30..194	CDD:206657	53/163 (33%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P10949	53..66		4/12 (33%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P10949	86..104		12/17 (71%)