DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CRMP and PYD2

DIOPT Version :9

Sequence 1:	NP_730954.2	Gene:	CRMP / 40675	FlyBaseID:	FBgn0023023	Length:	594	Species:	Drosophila melanogaster
Sequence 2:	NP_568258.2	Gene:	PYD2 / 831093	AraportID:	AT5G12200	Length:	531	Species:	Arabidopsis thaliana

Alignment Length:	482	Identity:	215/482 - (44%)
Similarity:	289/482 - (59%)	Gaps:	22/482 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 AQNRVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTH 82
            :..|:.||.|.:||......||||:|:|||..|.|:  |.:...|..:||:|..::|||||||||
plant    43 SSTRILIKGGTVVNAHHQELADVYVENGIIVAVQPN--IKVGDEVTVLDATGKFVMPGGIDPHTH 105

  Fly    83 MQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESM--IEAYDKWRSWADPKVCCDYGLH 145
            :.:.|.|...:|||:.|..||:||||||.||||:|.....:  .|||:.    ...:.|.|||.|
plant   106 LAMEFMGTETIDDFFSGQAAALAGGTTMHIDFVIPVNGNLVAGFEAYEN----KSRESCMDYGFH 166

  Fly   146 VGITWWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAENGD 210
            :.||.|.:.||.::.:|.||.|:||||.|:||||...:.|..||:..:|.:.|..:|||||||||
plant   167 MAITKWDEGVSRDMEMLVKEKGINSFKFFLAYKGSLMVTDDLLLEGLKRCKSLGALAMVHAENGD 231

  Fly   211 IIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELARAR 275
            .:.:..:|::..||.|||||.||||..:|.||..||..||...:.|||||||||..|..|:|:||
plant   232 AVFEGQKRMIELGITGPEGHALSRPPVLEGEATARAIRLARFINTPLYVVHVMSVDAMDEIAKAR 296

  Fly   276 HRYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRP---DKTTPEFLMKLLANDDLQL 337
            .  .|:.::||.:.:.|..|........|...:.:|:|||:||   .|.    |...|:...|||
plant   297 K--SGQKVIGEPVVSGLILDDHWLWDPDFTIASKYVMSPPIRPVGHGKA----LQDALSTGILQL 355

  Fly   338 TGSDNCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFN 402
            .|:|:||||...||||..||.:|||||||:|:||.|:|:..|.:|.|....:|.:|||..|:|||
plant   356 VGTDHCTFNSTQKALGLDDFRRIPNGVNGLEERMHLIWDTMVESGQLSATDYVRITSTECARIFN 420

  Fly   403 IYPQKGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAERGN 467
            |||:||.|..||||||:|.|||::..||..:||...|.|::||....|..|..:..|||..|...
plant   421 IYPRKGAILAGSDADIIILNPNSSYEISSKSHHSRSDTNVYEGRRGKGKVEVTIAGGRIVWENEE 485

  Fly   468 VRVAEGFGRFIPTPVRPPFVY--DIIE 492
            ::|....|::|.   .|||.|  |.||
plant   486 LKVVPRSGKYIE---MPPFSYLFDGIE 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CRMP	NP_730954.2	D-HYD	22..475	CDD:238639	205/457 (45%)
CRMP	NP_730954.2	PRK09060	24..483	CDD:181632	207/463 (45%)
PYD2	NP_568258.2	PLN02942	41..526	CDD:178530	215/482 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	339	1.000	Domainoid score	I243
eggNOG	1	0.900	-	-		E1_COG0044
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H20359
Inparanoid	1	1.050	383	1.000	Inparanoid score	I526
OMA	1	1.010	-	-		QHG54576
OrthoDB	1	1.010	-	-		D719800at2759
OrthoFinder	1	1.000	-	-		FOG0000315
OrthoInspector	1	1.000	-	-		oto3075
orthoMCL	1	0.900	-	-		OOG6_100676
Panther	1	1.100	-	-	LDO	PTHR11647
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X218
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840