Protein Alignment CRMP and dpysl2a

DIOPT Version :10

• Sequence 1: NP_730954.2
• Gene: CRMP / 40675
• FlyBaseID: FBgn0023023
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: XP_003199094.1
• Gene: dpysl2a / 798555
• ZFINID: ZDB-GENE-100914-5
• Length: 573
• Species: Danio rerio
• Alignment Length: 603
• Identity: 286/603 - (47%)
• Similarity: 381/603 - (63%)
• Gaps: 62/603 - (10%)

  Fly     9 KKVPIHLQSAQNRVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMII 73
            |.:|   :...:|:.||..:|||.|:||.||:|:|||:||.:|  ..:.:||||:.|:|.|.|:|
Zfish     8 KNIP---RITSDRLLIKGAKIVNDDQSFHADIYMEDGVIKQIG--ENLIVPGGVKIIEAHGRMLI 67

  Fly    74 PGGIDPHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKV 138
            |||||.||..|:|..|..|.||||.||:||:|||||||:|.|:|....|:|.|:::||.|||.|.
Zfish    68 PGGIDVHTRFQMPDRGMTAADDFYQGTRAALAGGTTMIMDHVVPEPGFSLISAFNQWREWADQKS 132

  Fly   139 CCDYGLHVGITWWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAM 203
            ||||.|||.||.|.|.:.|||.:|.|:.|||||..::|||.::|||||.:.:||..||.|..:|.
Zfish   133 CCDYSLHVDITEWHKGLQEEIEMLVKDHGVNSFLVYLAYKDIFQLNDSQMYEVFSVIRDLGAIAQ 197

  Fly   204 VHAENGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAG 268
            ||||||||||:..:|:|..||.|||||.||||||||||||:||..:|:|.:||||:..||||||.
Zfish   198 VHAENGDIIAEEQKRILGLGITGPEGHVLSRPEEVEAEAVNRAVTIANQTNCPLYITKVMSKSAA 262

  Fly   269 IELARARHRYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMKLLAND 333
            ..:|:||.  :|..:.||.::|:||||.|......:...||.:.||||.||.|||::|..|||..
Zfish   263 DVIAQARK--KGTVVYGEPISASLGTDGTHYWSKNWAKAAAFITSPPLSPDPTTPDYLNSLLACG 325

  Fly   334 DLQLTGSDNCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAA 398
            |||:|||.:||||...:|:||.:||.||.|.||.|:|||::|:|.|..|.:|..:||.|||||||
Zfish   326 DLQVTGSAHCTFNTSQRAVGKDNFTFIPEGTNGTEERMSIIWDKCVVTGKMDENQFVLVTSTNAA 390

  Fly   399 KIFNIYPQKGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICA 463
            ||||:||:|||||||||||:|:|:|:||:.||..:||.|.::||||||.|.|....|:.:|::..
Zfish   391 KIFNLYPRKGRIAVGSDADLVLWDPDATKIISAKSHHLAVEYNIFEGMEVRGAPLVVISQGKVVL 455

  Fly   464 ERGNVRVAEGFGRFIPTPVRPPFVYDIIEGKVQSQPEEQHEEKQNGSMAKRFAELDIQIPVQEPI 528
            |.||:...||.||:|.....|.:||..|:.:                  .|.|||
Zfish   456 EEGNLHTTEGSGRYISRKPFPDYVYKRIKAR------------------SRLAEL---------- 492

  Fly   529 SAMLAGNLAMPA---EGSLCS---TPSVRGRV-DGK-----------RDLQESSFSIS--EELDR 573
                   ..:|.   :|.:|.   ||.|...| .||           |:|.:|.||:|  :..|.
Zfish   493 -------RGVPRGLYDGPVCEVTVTPKVMTPVTSGKTSPVKPAPQPVRNLHQSGFSLSGAQVDDN 550

  Fly   574 SGVRACIKVKNPPGGKSS 591
            ...|...::..||||:::
Zfish   551 VPRRTTQRIVAPPGGRAN 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRMP	NP_730954.2	D-HYD	22..475	CDD:238639	251/452 (56%)
dpysl2a	XP_003199094.1	D-HYD	18..467	CDD:238639	251/452 (56%)