Protein Alignment CRMP and Dpysl5

DIOPT Version :10

• Sequence 1: NP_730954.2
• Gene: CRMP / 40675
• FlyBaseID: FBgn0023023
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_075412.1
• Gene: Dpysl5 / 65208
• RGDID: 620467
• Length: 564
• Species: Rattus norvegicus
• Alignment Length: 588
• Identity: 277/588 - (47%)
• Similarity: 360/588 - (61%)
• Gaps: 38/588 - (6%)

  Fly    17 SAQNRVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHT 81
            ||..|:.||.|::||.|.:.:||||||:|||:.||  .|:.||||.:.|||:|.::||||||..|
  Rat     5 SASVRILIKGGKVVNDDCTHEADVYIENGIIQQVG--RELMIPGGAKVIDATGKLVIPGGIDTST 67

  Fly    82 HMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGLHV 146
            |....|..|..|||||||||||:.|||||||..|||:|..|::|||:|.|:.|||||||||.|||
  Rat    68 HFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVEAYEKCRALADPKVCCDYALHV 132

  Fly   147 GITWWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAENGDI 211
            |||||:..|..|:..|.:|.|||||:.||.||.||.|.||:|..||...|....:..||||||::
  Rat   133 GITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVFHACRDFGAIPRVHAENGEL 197

  Fly   212 IAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELARARH 276
            :|:..:..|..||.||||.|:|.|||:||||.||...:|::..||:|:|:|.|.|||..:|.|
  Rat   198 VAEGAKEALDLGITGPEGIEISHPEELEAEATHRVITIANRTHCPIYLVNVSSISAGDVIAAA-- 260

  Fly   277 RYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMKLLANDDLQLTGSD 341
            :.:|:.::.||..|..........|..:...||:|..||||.|..|..:||.|||||.|.:..||
  Rat   261 KMQGKVVLAETTNAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASD 325

  Fly   342 NCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFNIYPQ 406
            :..|..:.||:||.||||||:||:||:||||:|||:||..|.:|..|||||||:|||||.|:||:
  Rat   326 HRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVVWERGVVGGKMDENRFVAVTSSNAAKILNLYPR 390

  Fly   407 KGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAERGNVRVA 471
            ||||..|:|||:|:|:|.||:|||..|.....|||::|.|..|||....:.|||:..|.|....|
  Rat   391 KGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCA 455

  Fly   472 EGFGRFIPTPVRPPFVYDIIEGKVQSQPEEQHEEKQNGSMAKRFAELDIQIPVQEPISAMLAGNL 536
            ||.|:|.|....|..||                        |:..:.:..:.|:........|::
  Rat   456 EGTGKFCPLRSFPDIVY------------------------KKLVQREKTLKVRGVDRTPYLGDV 496

  Fly   537 AM---PAEGS----LCSTPS-VRGRVDGKRDLQESSFSISEEL--DRSGVRACIKVKNPPGGKSS 591
            |:   |.:..    |..||: ...|..|.|||.|||||:|...  |....||..::..||||:||
  Rat   497 AVVVNPGKKEMGTPLADTPTRPVTRHGGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSS 561

  Fly   592 GFW 594
            |.|
  Rat   562 GIW 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRMP	NP_730954.2	D-HYD	22..475	CDD:238639	238/452 (53%)
Dpysl5	NP_075412.1	D-HYD	10..459	CDD:238639	238/452 (53%)