Protein Alignment CRMP and Dpys

DIOPT Version :10

• Sequence 1: NP_730954.2
• Gene: CRMP / 40675
• FlyBaseID: FBgn0023023
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_073559.3
• Gene: Dpys / 64705
• MGIID: 1928679
• Length: 519
• Species: Mus musculus
• Alignment Length: 486
• Identity: 286/486 - (58%)
• Similarity: 345/486 - (70%)
• Gaps: 14/486 - (2%)

  Fly    19 QNRVYIKNGEIVNHDKSFKADVYIEDGIIKFVG----PSSEITIPGGVRTIDASGLMIIPGGIDP 79
            |.|:.|:.|.|||.|.|..|||.:|||:::.:|    |..:.:  .|:|.:||:|.:::|||||.
Mouse     4 QGRLLIRGGRIVNDDFSQVADVLVEDGVVRALGRDLLPPEDAS--RGLRILDAAGKLVLPGGIDT 66

  Fly    80 HTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGL 144
            |||||.||.|:.:|||||.|||||:||||||||||.:|.|..|:|||::.||:||||||||||.|
Mouse    67 HTHMQFPFMGSQSVDDFYQGTKAALAGGTTMIIDFAIPQKGSSLIEAFETWRNWADPKVCCDYSL 131

  Fly   145 HVGITWWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAENG 209
            ||.:||||..|.||:..|.::.||||||.||||||||.:.|..|...|.:.:.:..:|.||||||
Mouse   132 HVAVTWWSDKVKEEMKTLARDKGVNSFKMFMAYKGLYMVQDEQLYAAFSQCKEIGAIAQVHAENG 196

  Fly   210 DIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELARA 274
            |:||:..:::||.||.|||||||.|||.|||||..||..:|...:|||||||||||||...:|.|
Mouse   197 DLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYVVHVMSKSAAKVVADA 261

  Fly   275 RHRYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMKLLANDDLQLTG 339
            |.  .|..:.||.:||.||||........:...|.||:.||||||..||.|||.||||.||..||
Mouse   262 RR--AGNVVYGEPIAAGLGTDGRQYWSEEWSHAAHHVMGPPLRPDPLTPGFLMDLLANGDLTTTG 324

  Fly   340 SDNCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFNIY 404
            |||||||...|||||.|||||||||||||||||::||||||:|.:|..|||||||||||||||:|
Mouse   325 SDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLY 389

  Fly   405 PQKGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAERGNVR 469
            |:|||||||||||||||:|.|||.||..|||.|.:|||||||..|||....:.|||:..|.|...
Mouse   390 PKKGRIAVGSDADIVIWDPEATRRISAKTHHQAVNFNIFEGMVCHGVPLVTISRGRVVYEAGVFN 454

  Fly   470 VAEGFGRFIPTPVRPPF---VYDIIEGKVQS 497
            |..|.|:|||   |.||   :|..|:.:.|:
Mouse   455 VTAGHGKFIP---RQPFAEYIYKRIKQRDQT 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRMP	NP_730954.2	D-HYD	22..475	CDD:238639	274/456 (60%)
Dpys	NP_073559.3	D-HYD	7..460	CDD:238639	274/456 (60%)