Protein Alignment: CRMP and DPYSL5

• Sequence 1: NP_730954.2
• Gene: CRMP
• FlyBaseID: FBgn0023023
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_001240652.1
• Gene: DPYSL5
• HGNCID: 20637
• Length: 564
• Species: Homo sapiens
• Alignment Length: 588
• Identity: 274/589 (47%)
• Similarity: 361/589 (61%)
• Gaps: 38/589 (6%)

  Fly    17 SAQNRVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHT 81
            ||..|:.||.|::||.|.:.:||||||:|||:.||  .|:.||||.:.|||:|.::||||||..|
Human     5 SASVRILIKGGKVVNDDCTHEADVYIENGIIQQVG--RELMIPGGAKVIDATGKLVIPGGIDTST 67

  Fly    82 HMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGLHV 146
            |....|..|..|||||||||||:.|||||||..|||:|..|:::||:|.|..|||||||||.|||
Human    68 HFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVDAYEKCRGLADPKVCCDYALHV 132

  Fly   147 GITWWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAENGDI 211
            |||||:..|..|:..|.:|.|||||:.||.||.||.|.||:|..|....:.:..:|.||||||::
Human   133 GITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVLHACKDIGAIARVHAENGEL 197

  Fly   212 IAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELARARH 276
            :|:..:..|..||.||||.|:|||||:||||.||...:|::..||:|:|:|.|.|||..:|.|
Human   198 VAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTHCPIYLVNVSSISAGDVIAAA-- 260

  Fly   277 RYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMKLLANDDLQLTGSD 341
            :.:|:.::.||..|..........|..:...||:|..||||.|..|..:||.|||||.|.:..||
Human   261 KMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASD 325

  Fly   342 NCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFNIYPQ 406
            :..|..:.||:||.||||||:||:||:||||::||:||..|.:|..|||||||:||||:.|:||:
Human   326 HRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWERGVVGGKMDENRFVAVTSSNAAKLLNLYPR 390

  Fly   407 KGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAERGNVRVA 471
            ||||..|:|||:|:|:|.||:|||..|.....|||::|.|..|||....:.|||:..|.|....|
Human   391 KGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCA 455

  Fly   472 EGFGRFIPTPVRPPFVYDIIEGKVQSQPEEQHEEKQNGSMAKRFAELDIQIPVQEPISAMLAGNL 536
            ||.|:|.|....|..||                        |:..:.:..:.|:........|::
Human   456 EGTGKFCPLRSFPDTVY------------------------KKLVQREKTLKVRGVDRTPYLGDV 496

  Fly   537 AM---PAEGS----LCSTPS-VRGRVDGKRDLQESSFSISEEL--DRSGVRACIKVKNPPGGKSS 591
            |:   |.:..    |..||: ...|..|.|||.|||||:|...  |....||..::..||||:||
Human   497 AVVVHPGKKEMGTPLADTPTRPVTRHGGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSS 561

  Fly   592 GFW 594
            |.|
Human   562 GIW 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRMP	NP_730954.2	D-HYD	22..475	CDD:238639	235/453 (52%)
		PRK09060	24..483	CDD:181632	238/459 (52%)
DPYSL5	NP_001240652.1	D-HYD	10..459	CDD:238639	235/453 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C61679936
eggNOG	1	0.900				E1_COG0044
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	571	1.000	Inparanoid score	I1039
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D174151at33208
OrthoFinder	1	1.000				FOG0000190
OrthoInspector	1	1.000				T609346
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR11647
Phylome	1	0.910		0.846	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	1	0.960
User_Submission	0	0.000	Not matched by this tool.
	10	9.860