Protein Alignment CRMP and dpysl4

DIOPT Version :10

• Sequence 1: NP_730954.2
• Gene: CRMP / 40675
• FlyBaseID: FBgn0023023
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: XP_021335783.1
• Gene: dpysl4 / 553411
• ZFINID: ZDB-GENE-050720-3
• Length: 675
• Species: Danio rerio
• Alignment Length: 584
• Identity: 282/584 - (48%)
• Similarity: 371/584 - (63%)
• Gaps: 41/584 - (7%)

  Fly    20 NRVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTHMQ 84
            :::.||.|:|||.|:||.||:|:||||||.:|  ..:.:|.||:|:||.|.::||||||.:|.:|
Zfish   116 DKLIIKGGKIVNDDQSFYADIYVEDGIIKQIG--ENLIVPTGVKTVDAYGHIVIPGGIDVNTCLQ 178

  Fly    85 LPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGLHVGIT 149
            .|..|....|||||||:||:|||||||||.|:|....|::.|:|:|:..||.:.||||.||:.||
Zfish   179 APHLGMSPADDFYHGTRAALAGGTTMIIDHVVPEPGSSLLSAFDQWKDTADKRSCCDYSLHIDIT 243

  Fly   150 WWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAENGDIIAK 214
            .|...:.||:..|.|:.|||||..|||||..:|.:|:.:.::|..:|.|..:|.|||||||||.:
Zfish   244 RWHDGLFEELESLVKDKGVNSFLIFMAYKDKFQSSDTQIYEMFSAMRELGAIAQVHAENGDIIEE 308

  Fly   215 NTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELARARHRYR 279
            ..::||..||.|||||.||.|||||.|||:||..:|.||:||||:..||||.|...:|:||.  :
Zfish   309 EQKKLLDLGITGPEGHVLSHPEEVETEAVYRAITIAKQANCPLYITKVMSKPAADLIAKARK--K 371

  Fly   280 GRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMKLLANDDLQLTGSDNCT 344
            |..|.||.:||:||||.:......:...||.|:||||.||.:||::|..||:..|||:|.|.|||
Zfish   372 GMVIYGEPIAASLGTDGSHYWSKNWAEAAAFVMSPPLNPDTSTPDYLNSLLSCGDLQVTASANCT 436

  Fly   345 FNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFNIYPQKGR 409
            |....||:||.|||.||.|.||:|:|||:||:|.|..|.:|...||||||||||||||:||:|||
Zfish   437 FTTAQKAVGKDDFTFIPEGTNGIEERMSIVWDKAVATGKMDENDFVAVTSTNAAKIFNLYPRKGR 501

  Fly   410 IAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAERGNVRVAEGF 474
            |||||||||||||...|||.|..||:...:.||||||...|....|:.:|||..|.|.:.|.||.
Zfish   502 IAVGSDADIVIWNTKETRTFSAKTHNLTVEVNIFEGMECRGFPVLVISQGRIVLEDGTLSVMEGS 566

  Fly   475 GRFIPTPVRPPFVYDIIEGKVQSQPEEQHEEKQNGSMAKRFAELDIQIPVQEPISAMLAGNLAMP 539
            |||||....|.:||..|  |.:|:..:          |:.....:...||.:.||.    ..::|
Zfish   567 GRFIPRKAYPDYVYKRI--KARSRMAD----------ARGVPRGNYDGPVHDVISM----TKSVP 615

  Fly   540 AEGSLCSTPSVRG-RVDGK------RDLQESSFSIS-----EELDRSGVRACIKVKNPPGGKSS 591
            |      ||:.|| ...||      |:|.:|.|::|     :.:.|   |...|:..||||:|:
Zfish   616 A------TPTTRGPSCPGKTPLGPTRNLHQSGFTLSGTQMDDHIPR---RTAQKIVAPPGGRSN 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRMP	NP_730954.2	D-HYD	22..475	CDD:238639	245/452 (54%)
dpysl4	XP_021335783.1	D-HYD	118..567	CDD:238639	245/452 (54%)