Protein Alignment CRMP and dpysl3

DIOPT Version :9

• Sequence 1: NP_730954.2
• Gene: CRMP / 40675
• FlyBaseID: FBgn0023023
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_001018348.1
• Gene: dpysl3 / 553166
• ZFINID: ZDB-GENE-050720-2
• Length: 567
• Species: Danio rerio
• Alignment Length: 596
• Identity: 284/596 - (47%)
• Similarity: 379/596 - (63%)
• Gaps: 53/596 - (8%)

  Fly     9 KKVPIHLQSAQNRVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMII 73
            |.:|   :....|:.||.|.|||.|:||.||:|:|||:||.:|  ..:.:||||:||:|:|.|:|
Zfish     7 KNIP---KITSERLLIKGGRIVNDDQSFYADIYMEDGVIKQIG--DNLIVPGGVKTIEANGKMVI 66

  Fly    74 PGGIDPHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKV 138
            |||||.|||:|:||.|....|||..|||||:|||||||:|.|:|....|::||:|:|..|||.|.
Zfish    67 PGGIDIHTHLQMPFRGTTTADDFTQGTKAALAGGTTMIVDHVIPEPGCSLLEAFDRWSKWADEKA 131

  Fly   139 CCDYGLHVGITWWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAM 203
            ||||.|||.||.|:.||.:|:..|.||.|||||:.:||:|.|||:::::|.:||..:....|:|.
Zfish   132 CCDYSLHVDITHWNDSVKQEVETLIKEKGVNSFQVYMAFKDLYQMSNTELYEVFTFLGEHGGIAQ 196

  Fly   204 VHAENGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAG 268
            ||||||:|||:...|:|..||.|||||.||||||:|||||.||..:|.|.:|||||..||||||.
Zfish   197 VHAENGEIIAEEQARMLEMGITGPEGHVLSRPEELEAEAVFRAVTIASQTNCPLYVTRVMSKSAA 261

  Fly   269 IELARARHRYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMKLLAND 333
            ..:::||.  :|..:.||.:.|:||||.|......:...|:.|.||||.||.|||::|..|||:.
Zfish   262 DIISQARK--KGNVVFGEPITASLGTDGTHYWSKNWAKAASFVTSPPLSPDPTTPDYLNTLLASG 324

  Fly   334 DLQLTGSDNCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAA 398
            ||.:.||.:|||:...||:||.|||:||.||||.|:|||::|:|.|..|.:|...||||||||||
Zfish   325 DLSVVGSAHCTFSVAQKAIGKDDFTQIPEGVNGAEERMSIIWDKAVVTGKMDENMFVAVTSTNAA 389

  Fly   399 KIFNIYPQKGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICA 463
            ||.|:||:|||||||||:|:|||:.:|.|||:..|||.|.::|:||||.:.|....|:.:|:|..
Zfish   390 KILNLYPRKGRIAVGSDSDLVIWDTDAVRTITAKTHHSAAEYNVFEGMELRGAPMLVVCQGKIVL 454

  Fly   464 ERGNVRVAEGFGRFIPTPVRPPFVYDIIEGKVQ-----SQPEEQHEEKQNGSMAKRFAELDIQIP 523
            |.||:....|.|||||....|.|.|..::.:.|     :.|...::.                 |
Zfish   455 EDGNLHATSGTGRFIPCSPFPDFAYKRVKARKQLAILKAVPRGMYDG-----------------P 502

  Fly   524 VQEPISAMLAGNLAMPAEGSLCSTPSVRGRVDGK----RDLQESSFSIS--EE--LDRSGVRACI 580
            |.| .|.|..|           .|||...|....    |:|.:|.|::|  ||  :..:|.|..:
Zfish   503 VSE-FSPMSRG-----------GTPSASTRTSPTKVPVRNLHQSGFTLSGPEEAPIRPAGRRIVV 555

  Fly   581 KVKNPPGGKSS 591
                ||||:|:
Zfish   556 ----PPGGRSN 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRMP	NP_730954.2	D-HYD	22..475	CDD:238639	247/452 (55%)
		PRK09060	24..483	CDD:181632	252/458 (55%)
dpysl3	NP_001018348.1	PRK09060	17..467	CDD:181632	247/453 (55%)
		D-HYD	17..466	CDD:238639	247/452 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	505..567		22/74 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	501	1.000	Domainoid score	I338
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	561	1.000	Inparanoid score	I1059
OMA	1	1.010	-	-		QHG54576
OrthoDB	1	1.010	-	-		D174151at33208
OrthoFinder	1	1.000	-	-		FOG0000315
OrthoInspector	1	1.000	-	-		otm24326
orthoMCL	1	0.900	-	-		OOG6_100676
Panther	1	1.100	-	-	O	PTHR11647
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5547
SonicParanoid	1	1.000	-	-		X218
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	12.010