Protein Alignment CRMP and dpysl4

DIOPT Version :10

• Sequence 1: NP_730954.2
• Gene: CRMP / 40675
• FlyBaseID: FBgn0023023
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: XP_031760913.1
• Gene: dpysl4 / 548482
• XenbaseID: XB-GENE-960292
• Length: 668
• Species: Xenopus tropicalis
• Alignment Length: 593
• Identity: 282/593 - (47%)
• Similarity: 375/593 - (63%)
• Gaps: 60/593 - (10%)

  Fly    20 NRVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTHMQ 84
            :|:.||.|:|||.|:||.||:|||||:||.:|  ..:.:||||:||||.||::||||||.||.:|
 Frog   110 DRLLIKGGKIVNDDQSFLADIYIEDGLIKQIG--ENLIVPGGVKTIDAHGLLVIPGGIDVHTRLQ 172

  Fly    85 LPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGLHVGIT 149
            :|..|..:.|||:.|||||:|||||||||.|.|:...::::|||:||.|||.||||||.|||.||
 Frog   173 MPVMGMTSADDFFQGTKAALAGGTTMIIDHVFPDSGMNLVQAYDQWREWADGKVCCDYSLHVDIT 237

  Fly   150 WWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAENGDIIAK 214
            :|.:|:.||:..|.|:.|||||..|||||..||..|:::.::|..||.|..:|.|||||||||.:
 Frog   238 YWHESLKEELEALVKDKGVNSFLVFMAYKDQYQCTDAEMYEIFSIIRDLGAIAQVHAENGDIIQE 302

  Fly   215 NTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELARARHRYR 279
            ..:|:|..||.|||||.||.||||||||.:||..:|.||:||||:..|||:.|...:|:|:.  :
 Frog   303 EQKRMLECGITGPEGHVLSHPEEVEAEAAYRAITIAKQANCPLYITKVMSRGAADVIAQAKR--K 365

  Fly   280 GRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMKLLANDDLQLTGSDNCT 344
            |..:.||||.|::|||.|......:...||:|.|||:.||.:||:.|..||:..||.:|||.:||
 Frog   366 GIVVYGETLTASIGTDGTHYWSKNWAKAAAYVTSPPISPDPSTPDHLTSLLSCGDLHVTGSAHCT 430

  Fly   345 FNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFNIYPQKGR 409
            |....||:||.:|..||.|.||:|:||:::|:|.|.:|.:|...|||||||||||:||:||:|||
 Frog   431 FTTAQKAVGKDNFILIPEGTNGIEERMTIIWDKCVTSGKMDENAFVAVTSTNAAKLFNLYPRKGR 495

  Fly   410 IAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAERGNVRVAEGF 474
            ||.|||||:|||||...:.||..||:...:.||||||..||..|.|:.:|||..|.||:.|::|.
 Frog   496 IATGSDADLVIWNPKTAKIISAKTHNMNVELNIFEGMECHGAPEVVISQGRIVLEDGNLHVSQGS 560

  Fly   475 GRFIPTPVRPPFVYDIIEGKVQSQPEEQHEEKQNGSMAKRFAEL-------------DIQIPVQE 526
            |||:|....|.:||..|:.:                  .|.||:             |:.|..:
 Frog   561 GRFVPRKTFPDYVYKRIKAR------------------NRLAEIRGVPRGLYDGPVHDVTITTK- 606

  Fly   527 PISAMLAGNLAMPAEGSLCSTPSVRGRVDGK------RDLQESSFSI--SEELDRSGVRACIKVK 583
                            |..|||:.|....||      |:|..|.||:  |:|.|....|...|:.
 Frog   607 ----------------SAASTPASRIACPGKIQMGPVRNLHHSGFSLSGSQEDDHVPRRTTQKIV 655

  Fly   584 NPPGGKSS 591
            .||||:|:
 Frog   656 APPGGRSN 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRMP	NP_730954.2	D-HYD	22..475	CDD:238639	246/452 (54%)
dpysl4	XP_031760913.1	D-HYD	112..561	CDD:238639	246/452 (54%)