Protein Alignment CRMP and Dpysl2

DIOPT Version :10

• Sequence 1: NP_730954.2
• Gene: CRMP / 40675
• FlyBaseID: FBgn0023023
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: XP_006252159.1
• Gene: Dpysl2 / 25416
• RGDID: 2517
• Length: 673
• Species: Rattus norvegicus
• Alignment Length: 604
• Identity: 286/604 - (47%)
• Similarity: 379/604 - (62%)
• Gaps: 51/604 - (8%)

  Fly     9 KKVPIHLQSAQ----------NRVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVR 63
            :||.|...|.:          :|:.||.|:|||.|:||.||:|:|||:||.:|  ..:.:||||:
  Rat    95 RKVEIRRASGKEALQNIYDQSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIG--ENLIVPGGVK 157

  Fly    64 TIDASGLMIIPGGIDPHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYD 128
            ||:|...|:||||||.||..|:|..|..:.|||:.|||||:|||||||||.|:|....|::.|:|
  Rat   158 TIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFD 222

  Fly   129 KWRSWADPKVCCDYGLHVGITWWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFE 193
            :||.|||.|.||||.|||.||.|.|.:.||:..|.|:.|||||..:||:|..:||.||.:.:|..
  Rat   223 QWREWADSKSCCDYSLHVDITEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDSQIYEVLS 287

  Fly   194 RIRHLNGVAMVHAENGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLY 258
            .||.:..:|.||||||||||:..||:|..||.|||||.||||||||||||:|:..:|:|.:||||
  Rat   288 VIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRSITIANQTNCPLY 352

  Fly   259 VVHVMSKSAGIELARARHRYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTP 323
            |..||||||...:|:||.  :|..:.||.:.|:||||.:......:...||.|.||||.||.|||
  Rat   353 VTKVMSKSAAEVIAQARK--KGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTP 415

  Fly   324 EFLMKLLANDDLQLTGSDNCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCR 388
            :||..||:..|||:|||.:||||...||:||.:||.||.|.||.|:|||::|:|.|..|.:|..:
  Rat   416 DFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQ 480

  Fly   389 FVAVTSTNAAKIFNIYPQKGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCE 453
            |||||||||||:||:||:||||:||||||:|||:|::.:|||..||:.|.::||||||...|...
  Rat   481 FVAVTSTNAAKVFNLYPRKGRISVGSDADLVIWDPDSVKTISAKTHNSALEYNIFEGMECRGSPL 545

  Fly   454 FVLVRGRICAERGNVRVAEGFGRFIPTPVRPPFVYDIIEGKVQSQPEEQHEEKQNGSMAKRFAEL 518
            .|:.:|:|..|.|.:.|.||.||:||....|.|||..|:.:                  .|.|||
  Rat   546 VVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKAR------------------SRLAEL 592

  Fly   519 D------IQIPVQEPISAMLAGNLAMPAEGSLCSTPSVRGRVDGKRDLQESSFSIS-----EELD 572
            .      ...||.|   ..:......||  |...|...:.:....|:|.:|.||:|     :.:.
  Rat   593 RGVPRGLYDGPVCE---VSVTPKTVTPA--SSAKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIP 652

  Fly   573 RSGVRACIKVKNPPGGKSS 591
            |   |...::..||||:::
  Rat   653 R---RTTQRIVAPPGGRAN 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRMP	NP_730954.2	D-HYD	22..475	CDD:238639	249/452 (55%)
Dpysl2	XP_006252159.1	D-HYD	118..567	CDD:238639	249/452 (55%)