Protein Alignment: CRMP and DPYSL2

• Sequence 1: NP_730954.2
• Gene: CRMP
• FlyBaseID: FBgn0023023
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_001184222.1
• Gene: DPYSL2
• HGNCID: 3014
• Length: 677
• Species: Homo sapiens
• Alignment Length: 589
• Identity: 279/590 (47%)
• Similarity: 374/590 (63%)
• Gaps: 41/590 (7%)

  Fly    14 HLQSAQNRVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGID 78
            ::....:|:.||.|:|||.|:||.||:|:|||:||.:|  ..:.:||||:||:|...|:||||||
Human   114 NINDQSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIG--ENLIVPGGVKTIEAHSRMVIPGGID 176

  Fly    79 PHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYG 143
            .||..|:|..|..:.|||:.|||||:|||||||||.|:|....|::.|:|:||.|||.|.||||.
Human   177 VHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYS 241

  Fly   144 LHVGITWWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAEN 208
            |||.|:.|.|.:.||:..|.|:.|||||..:||:|..:||.|..:.:|...||.:..:|.|||||
Human   242 LHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQIYEVLSVIRDIGAIAQVHAEN 306

  Fly   209 GDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELAR 273
            |||||:..||:|..||.|||||.||||||||||||:||..:|:|.:||||:..|||||:...:|:
Human   307 GDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAITIANQTNCPLYITKVMSKSSAEVIAQ 371

  Fly   274 ARHRYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMKLLANDDLQLT 338
            ||.  :|..:.||.:.|:||||.:......:...||.|.||||.||.|||:||..||:..|||:|
Human   372 ARK--KGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVT 434

  Fly   339 GSDNCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFNI 403
            ||.:||||...||:||.:||.||.|.||.|:|||::|:|.|..|.:|..:|||||||||||:||:
Human   435 GSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNL 499

  Fly   404 YPQKGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAERGNV 468
            ||:|||||||||||:|||:|::.:|||..||:.:.::||||||...|....|:.:|:|..|.|.:
Human   500 YPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTL 564

  Fly   469 RVAEGFGRFIPTPVRPPFVYDIIEGKVQSQPEEQHEEKQNGSMAKRFAELD------IQIPVQEP 527
            .|.||.||:||....|.|||..|:.:                  .|.|||.      ...||.|
Human   565 HVTEGSGRYIPRKPFPDFVYKRIKAR------------------SRLAELRGVPRGLYDGPVCE- 610

  Fly   528 ISAMLAGNLAMPAEGSLCSTPSVRGRVDGKRDLQESSFSIS-----EELDRSGVRACIKVKNPPG 587
              ..:......||  |...|...:.:....|:|.:|.||:|     :.:.|   |...::..|||
Human   611 --VSVTPKTVTPA--SSAKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPR---RTTQRIVAPPG 668

  Fly   588 GKSS 591
            |:::
Human   669 GRAN 672

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRMP	NP_730954.2	D-HYD	22..475	CDD:238639	246/453 (54%)
		PRK09060	24..483	CDD:181632	250/459 (54%)
DPYSL2	NP_001184222.1	D-HYD	122..571	CDD:238639	246/453 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C61716404
eggNOG	1	0.900				E1_COG0044
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	571	1.000	Inparanoid score	I1039
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D174151at33208
OrthoFinder	1	1.000				FOG0000190
OrthoInspector	1	1.000				T609346
orthoMCL	1	0.900				OOG5_127801
Panther	1	1.100			O	PTHR11647
Phylome	1	0.910		0.846	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.800