Protein Alignment: CRMP and DPYS

• Sequence 1: NP_730954.2
• Gene: CRMP
• FlyBaseID: FBgn0023023
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: XP_005250875.1
• Gene: DPYS
• HGNCID: 3013
• Length: 555
• Species: Homo sapiens
• Alignment Length: 511
• Identity: 281/512 (55%)
• Similarity: 348/512 (68%)
• Gaps: 49/512 (10%)

  Fly    17 SAQNRVYIKNGEIVNHDKSFKADVYIEDGIIKFVG-----PSSEITIPGGVRTIDASGLMIIPGG 76
            :|.:|:.|:.|.:||.|.|..|||.:|||:::.:|     |..   .|.|:|.:||:|.:::|||
Human     2 AAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGG---APAGLRVLDAAGKLVLPGG 63

  Fly    77 IDPHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCD 141
            ||.|||||.||.|:.::|||:.|||||::|||||||||.:|.|..|:|||::.||||||||||||
Human    64 IDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCD 128

  Fly   142 YGLHVGITWWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHA 206
            |.|||.:||||..|.||:.||.::.||||||.|||||.||.:.|.:|.:.|.|.:.:..:|.|||
Human   129 YSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHA 193

  Fly   207 ENGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIEL 271
            ||||:||:..:::||.||.|||||||.|||.|||||..||..:|...:||||:||||||||...:
Human   194 ENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVI 258

  Fly   272 ARARHRYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMKLLANDDLQ 336
            |.||.  .|:.:.||.:||:||||.|...:..:...|.||:.||||||.:||:|||.|||||||.
Human   259 ADARR--DGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLT 321

  Fly   337 LTGSDNCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIF 401
            .||:||||||...|||||.|||||||||||||||||::||||||:|.:|..||||||||||||||
Human   322 TTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIF 386

  Fly   402 NIYPQKGRIAVGSDADIVIWNPNAT------------------------------------RTIS 430
            |:||:|||||||||||||||:|..|                                    ||||
Human   387 NLYPRKGRIAVGSDADIVIWDPKGTRGCRSCVAFSDNGSVYKTNMNLPLQCLANARVHMEERTIS 451

  Fly   431 KDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAERGNVRVAEGFGRFIPTPVRPPF 486
            ..|||.|.:|||||||..|||....:.||::..|.|...|..|.|:|||   |.||
Human   452 AKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIP---RKPF 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRMP	NP_730954.2	D-HYD	22..475	CDD:238639	272/494 (55%)
		PRK09060	24..483	CDD:181632	276/500 (55%)
DPYS	XP_005250875.1	D-HYD	7..496	CDD:238639	272/494 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C61700413
eggNOG	1	0.900				E1_COG0044
Hieranoid	1	1.000
Homologene	1	1.000				H20359
Inparanoid	1	1.050	571	1.000	Inparanoid score	I1039
Isobase	1	0.950		0.917438	Normalized mean entropy	S1869
OMA	1	1.010
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0000190
OrthoInspector	1	1.000				T609346
orthoMCL	1	0.900				OOG5_127801
Panther	1	1.100			LDO	PTHR11647
Phylome	1	0.910		0.846	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R5547
TreeFam	1	0.960
User_Submission	0	0.000	Not matched by this tool.
	14	13.740