Protein Alignment CRMP and dhp-2

DIOPT Version :10

• Sequence 1: NP_730954.2
• Gene: CRMP / 40675
• FlyBaseID: FBgn0023023
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_501797.1
• Gene: dhp-2 / 177852
• WormBaseID: WBGene00000964
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 569
• Identity: 292/569 - (51%)
• Similarity: 364/569 - (63%)
• Gaps: 57/569 - (10%)

  Fly    24 IKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTHMQLPFG 88
            ||||.|||.|..||:||.:.||.|..:.||.:.|  .|:..:||:..::|||||||||||||||.
 Worm     5 IKNGTIVNDDAIFKSDVLVLDGRIVEIAPSIQPT--PGLEVVDATDRLVIPGGIDPHTHMQLPFM 67

  Fly    89 GAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGLHVGITWWSK 153
            |.:|.|||:.||:||||||||||||||:|.|.||::.|||:||.||||||.|||||.:.||.|..
 Worm    68 GEIAKDDFHRGTEAAVAGGTTMIIDFVIPTKGESLLVAYDRWRGWADPKVVCDYGLSMAITSWGP 132

  Fly   154 SVSEEIGILC-KELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAENGDIIAKNTQ 217
            .:::|:.|:. .|.|:||||.|:||.|::.:.|.:......:...|..:|.||||||.:||:..:
 Worm   133 EIAKEMEIVTGAEYGINSFKFFLAYAGVFMVRDEEFYQGMIQCAKLRALARVHAENGSVIAERCE 197

  Fly   218 RLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELARARHRYRGRY 282
            .||:.||.|||||..|||||:||||..|||.:|.||:|||||||||||  |...|.|.||.:|..
 Worm   198 HLLSSGITGPEGHTQSRPEELEAEATFRACTMASQANCPLYVVHVMSK--GAAAAIAHHRKKGAV 260

  Fly   283 IMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMKLLANDDLQLTGSDNCTFNK 347
            :.||.:||.|.||.:...:..:...|.:|:||||..|.:||..||||||..:|.||.:|||||:.
 Worm   261 VFGEPIAAGLATDGSHYYNEDWLHAARYVMSPPLSRDPSTPSALMKLLAAGELHLTATDNCTFDC 325

  Fly   348 EHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFNIYPQKGRIAV 412
            :.|:|||.|||||||||||||||||:||:||||||::||.||||||||.||||||.|||||||||
 Worm   326 QQKSLGKDDFTKIPNGVNGVEDRMSVVWDKGVHAGIIDPMRFVAVTSTMAAKIFNCYPQKGRIAV 390

  Fly   413 GSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAERGNVRVAEGFGRF 477
            ||||||||||.||||||||||||||.||||||||.||||.|..:.|||.....|.::..:|.|:|
 Worm   391 GSDADIVIWNANATRTISKDTHHHAIDFNIFEGMQVHGVPEITISRGRTVWANGQLKTVQGSGQF 455

  Fly   478 IPTPVRPPFVYDIIEGKVQSQPEEQHEEKQNGSMAKRFAELDIQIPVQEPISAMLAGNLAMPAEG 542
            ||.......|:..::.:.::                           .||:...     .:|.|.
 Worm   456 IPLAPDSQIVFSAVDNRKKA---------------------------MEPVKID-----RIPYEP 488

  Fly   543 SLCSTPSVRGRVDGKRDLQESSFSISEELDRSGVRACIKVKNPPGGKSS 591
            |...||.....:                :.::.|||.|    ||||.||
 Worm   489 SALQTPDANANI----------------VVKAPVRAAI----PPGGASS 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRMP	NP_730954.2	D-HYD	22..475	CDD:238639	270/451 (60%)
dhp-2	NP_501797.1	D-HYD	3..453	CDD:238639	270/451 (60%)