Protein Alignment CRMP and dhp-1

DIOPT Version :10

• Sequence 1: NP_730954.2
• Gene: CRMP / 40675
• FlyBaseID: FBgn0023023
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_001021583.1
• Gene: dhp-1 / 172464
• WormBaseID: WBGene00000963
• Length: 489
• Species: Caenorhabditis elegans
• Alignment Length: 480
• Identity: 271/480 - (56%)
• Similarity: 338/480 - (70%)
• Gaps: 8/480 - (1%)

  Fly    24 IKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTHMQLPFG 88
            ||||.:||.|..|||||.:.:|||..|.|:  ||.......|||:..::||||||||||||:|:.
 Worm     7 IKNGTVVNEDGMFKADVLVRNGIIVEVSPN--ITALPDTEVIDATDRLVIPGGIDPHTHMQMPYM 69

  Fly    89 GAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKH--ESMIEAYDKWRSWADPKVCCDYGLHVGITWW 151
            |.|..|||..||:|||||||||||||..|:..  ||:|..|::|||||||||||||||.|.||.|
 Worm    70 GEVTKDDFLKGTEAAVAGGTTMIIDFCCPDHRNGESLIAGYNRWRSWADPKVCCDYGLSVAITMW 134

  Fly   152 SKSVSEEIGILCK-ELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAENGDIIAKN 215
            ....:|::.|:.. |.||||||.:|||:....:.|.:|....:....|..:|.||.|||.:|.:.
 Worm   135 RPETAEQMAIITSPEFGVNSFKFYMAYENTLMVRDDELFRGMQECAKLRALARVHCENGSVIKEK 199

  Fly   216 TQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELARARHRYRG 280
            ...|||:|:.|||||..|||||:||||.:||||||.||:||:|:||||:|  |...|.:.||.:|
 Worm   200 EIDLLAKGVTGPEGHTQSRPEEIEAEATNRACVLAAQANCPVYIVHVMTK--GAASAISHHRAQG 262

  Fly   281 RYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMKLLANDDLQLTGSDNCTF 345
            ..:.||.:||.|..|.:...:..:...|.:|:||||..|.||||.||||||..:|.|||:||||:
 Worm   263 SIVFGEPIAAGLALDGSHYYNEDWLHAARYVMSPPLSRDPTTPELLMKLLAAGELHLTGTDNCTY 327

  Fly   346 NKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFNIYPQKGRI 410
            :...|:||||:|||||||:||||||||:|||||||:|::||.|:|::||:.|||||||||:||||
 Worm   328 DCRQKSLGKGNFTKIPNGINGVEDRMSVVWEKGVHSGIIDPMRYVSITSSTAAKIFNIYPRKGRI 392

  Fly   411 AVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAERGNVRVAEGFG 475
            ||||||||||:|||||||||||||||..|||||||:..|||.|..:.||||....|.::...|.|
 Worm   393 AVGSDADIVIFNPNATRTISKDTHHHNLDFNIFEGINCHGVAEVTISRGRIVWAHGKLQTVPGSG 457

  Fly   476 RFIPTPVRPPFVYDIIEGKVQS-QP 499
            :|||.....|||:...|.:.|. ||
 Worm   458 KFIPLLANSPFVFSTHEKREQKIQP 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRMP	NP_730954.2	D-HYD	22..475	CDD:238639	260/453 (57%)
dhp-1	NP_001021583.1	D-HYD	5..457	CDD:238639	260/453 (57%)