Protein Alignment CRMP and XB5950266

DIOPT Version :9

• Sequence 1: NP_730954.2
• Gene: CRMP / 40675
• FlyBaseID: FBgn0023023
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: XP_031758421.1
• Gene: XB5950266 / 100498039
• XenbaseID: XB-GENE-5950267
• Length: 496
• Species: Xenopus tropicalis
• Alignment Length: 509
• Identity: 135/509 - (26%)
• Similarity: 208/509 - (40%)
• Gaps: 89/509 - (17%)

  Fly    24 IKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTHMQLPFG 88
            :::..:|..:....||:.|:||.|..:.|..:.:|..|.:.:||..|:::||.||||.|:..|
 Frog    42 VRSRRVVTGNTISPADIIIKDGKIVGIQPWGKQSITVGSQLLDAGDLVVMPGIIDPHVHVNEP-- 104

  Fly    89 GAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGLHVGITWWSK 153
            |....:.:...|:||.|||.|.|:|..|.:...:...:....:..|....|     .|.:.:|..
 Frog   105 GRTDWEGYSTATRAAAAGGITTIVDMPLNSLPPTTSVSNFLTKLKAAEGQC-----FVDVAFWGG 164

  Fly   154 SVS----EEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHL---NGVAMVHAE---- 207
            .:.    |.:.:|  ..||..||.|:...|:.:.....|:|:...:..|   |.|.:.|||
 Frog   165 VIPGNQLELVPML--HAGVAGFKCFLISSGVPEFPHVSLMDLHSAMSELQGTNSVLLFHAEFDDP 227

  Fly   208 -----NGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMS--- 264
                 |||.:...|  .||           |||..:|..||.....|..|.....::||:.|
 Frog   228 SRAPTNGDPMQYET--FLA-----------SRPPHMEVAAVEAVANLCLQYKVRCHIVHLSSAMA 279

  Fly   265 -------KSAGIEL-ARARHRYRGRYIMGETLAA-ALGTDAT---CCQHLGFDAEAAHVLSPPLR 317
                   |.||..| ....|.|.       ||:| .:...||   ||              ||:|
 Frog   280 LPIIRKAKKAGAPLTVETTHHYL-------TLSAEKIPPGATYFKCC--------------PPVR 323

  Fly   318 PDKTTPEFLMKLLANDDLQLTGSDNCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAG 382
             :.:..|.|...|....:.:..||:.....:.|.|..|||.|...|:..::..:||.|......|
 Frog   324 -EHSNKEALWNALLQGHIDMVVSDHSPCTPDLKLLQDGDFLKAWGGICSLQLGLSLFWSSARSRG 387

  Fly   383 --LLDPCRFVAVTSTNAAKIFNIYPQKGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEG 445
              |||..|.:   |:|.||:.::..:||.|..|.|||:|||:|:....:.:.:.||......:.|
 Frog   388 FSLLDIPRLL---SSNPAKLSSLDGRKGAIKPGYDADLVIWDPDKEYQVHEASLHHKNKLTPYLG 449

  Fly   446 MTVHGVCEFVLVRGRICAERGNVRVAEGFGRFIPTPVRPPFVYDIIEGKVQSQP 499
            ..:.|..|..:|.|.:...:         ||..|.|...|.:...:|....|.|
 Frog   450 FQLCGETEATIVGGILVYYK---------GRHCPVPAGKPLLIQTMELPEPSDP 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRMP	NP_730954.2	D-HYD	22..475	CDD:238639	127/483 (26%)
XB5950266	XP_031758421.1	metallo-dependent_hydrolases	41..482	CDD:469705	132/495 (27%)